196952-93-9

Basic information

• Product Name: 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI)
• Synonyms: 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI)
• CAS NO: 196952-93-9
• Molecular Formula: C10H7FO
• Molecular Weight: 162.1603832
• Product Categories: HALIDE
• Mol File: 196952-93-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI)(196952-93-9)
• EPA Substance Registry System: 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI)(196952-93-9)

Safety Data

• Hazardous Substances Data: 196952-93-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI) is used as a building block in the synthesis of various organic compounds. Its unique structure and the presence of the fluorine atom make it a valuable intermediate for the development of new chemical compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI) is used as a key intermediate in the production of various pharmaceuticals. The incorporation of the fluorine atom in the compound can enhance the properties and effectiveness of the resulting drugs.
Used in Agrochemical Industry:
2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI) is also used in the agrochemical industry as a precursor for the synthesis of various agrochemicals. The unique properties of the compound can contribute to the development of more effective and targeted agrochemicals.
Used as a Reagent in Chemical Research:
In addition to its applications in the synthesis of various compounds, 2,3-Butadien-1-one,1-(2-fluorophenyl)-(9CI) is also used as a reagent in the development of new chemical compounds and materials. Its unique structure and reactivity make it a valuable tool in chemical research and development.

Upstream product

• 446-52-6 2-Fluorobenzaldehyde 
• 1223611-84-4 1-(o-fluorophenyl)but-3-yn-1-ol 

Relevant articles and documents

Tandem reactions of 1,2-allenic ketones leading to substituted benzenes and α,β-unsaturated nitriles

One-pot double Michael addition/intramolecular aldol reaction/ decarboxylation of 1,2-allenic ketones with cyanoacetate offers an efficient and convenient approach to highly functionalized benzenes. With 2-substituted cyanoacetates, the reaction proceeds via a different tandem process to afford α,β-unsaturated nitriles effectively.

Ru(III)-catalyzed oxidation of homopropargyl alcohols in ionic liquid: an efficient and green route to 1,2-allenic ketones

An efficient and environmentally benign synthesis of 1,2-allenic ketones via RuCl3-catalyzed oxidation of homopropargyl alcohols in ionic liquid with tert-butyl hydroperoxide (TBHP) as the oxidant was reported for the first time. With its reasonable efficiency and green nature, this oxidation provides a novel alternative route to 1,2-allenic ketones.

C-C-Bond Formation by the Palladium-Catalyzed Cycloisomerization/Dimerization of Terminal Allenyl Ketones: Selectivity and Mechanistic Aspects

The scope of the palladium-catalyzed cyclization/dimerization of terminal allenyl ketones 1 to the 2,4-disubstituted furans 3 has been investigated. Simplified and improved conditions almost exclusively provided the dimer 3, accompanied by only traces of the easily separable monomer 2. The formation of an isomer of 3, the unconjugated ketone 4, was completeley suppressed. Under these mild conditions, besides the normal functional group tolerance known for palladium-catalyzed reactions, an interesting selectivity was observed with functional groups that are known to react either in palladium-catalyzed reactions or reactions catalyzed by other transition-metals. Thus aryl halides, terminal alkynes, 1,6-enynes, and α-allenic alcohols were tolerated. In the latter example the selective reaction of only one out of two different allenes was achieved. Mechanistic investigation indicated a Pd(II)/Pd(IV)-cycle involving palladium(II)-γ-alkoxyvinylcarbene and furylpalladium(IV) hydride intermediates, although a second pathway for the formation of the dimer 3 which also involves Pd(IV)-intermediates like the 3,4-dimethylenepalladacyclopentane 23 and the 3-methylenepalladacyclobutane-like structure 15 (respectively 25) could not completely be excluded.