19752-55-7

Basic information

• Product Name: 1-Bromo-3,5-dichlorobenzene
• Synonyms: 1-Bromo-3,5-dichlorobenzene,98%;1-Bromo-3,5-dichloro;5-DichlorobroMobenzene;1-bromo-3,5-dichloro-benzen;3,5-dichloro-1-bromobenzene;3,5-DICHLOROBROMOBENZENE;1-BROMO-3,5-DICHLOROBENZENE;BENZENE,1-BROMO-3,5-DICHLORO
• CAS NO: 19752-55-7
• Molecular Formula: C₆H₃BrCl₂
• Molecular Weight: 225.9
• EINECS: 243-270-7
• Product Categories: Aryl;C6;Halogenated Hydrocarbons;Fluorobenzene;Benzene derivates;Miscellaneous;Bromine Compounds;Chlorine Compounds
• Mol File: 19752-55-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 73-75 °C(lit.)
• Boiling Point: 232 °C757 mm Hg(lit.)
• Flash Point: 232°C
• Appearance: White to beige-brown/Crystalline Powder
• Density: 1.6351 (rough estimate)
• Vapor Pressure: 0.0998mmHg at 25°C
• Refractive Index: 1.5700 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1931524
• CAS DataBase Reference: 1-Bromo-3,5-dichlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-3,5-dichlorobenzene(19752-55-7)
• EPA Substance Registry System: 1-Bromo-3,5-dichlorobenzene(19752-55-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 19752-55-7(Hazardous Substances Data)

Usage

Chemical Properties

white to beige-brown crystalline powder

Uses

1-Bromo-3,5-dichlorobenzene, is a building block used in the synthesis of halogenated chemical compounds, such as polychlorinated biphenyls (PCBs).

General Description

1-Bromo-3,5-dichlorobenzene on treatment with iPrMgCl.LiCl in THF and then DMF at 0°C, followed by the reaction with molecular iodine and aq NH3 yields the corresponding aromatic nitrile.

InChI:InChI=1/C6H3BrCl2/c7-4-1-5(8)3-6(9)2-4/h1-3H

Upstream product

• 19393-97-6 1.4-Dibrom-2.6-dichlor-benzol 
• 62720-30-3 5-bromo-1,3-dichloro-2-iodobenzene 
• 626-43-7 3,5-Dichloroaniline 
• 63352-99-8 (3,5-dichlorophenyl)hydrazine hydrochloride 
• 554-00-7 2,4-Dichloroaniline 
• 106-95-6 allyl bromide 
• 697-86-9 2,4-dichloro-6-bromoaniline 
• 64-17-5 ethanol 

Downstream Products

• 99979-70-1 1-bromo-3,5-dichloro-2,4-dinitro-benzene 
• 54773-20-5 1,3-dichloro-5-(trifluoromethyl)benzene 
• 160515-02-6 pentamethyl-(3,3'-dichlorophenyl)disilane 
• 130336-16-2 3,5-dichloro-2,2,2-trifluoroacetophenone 
• 38444-87-0 3,5,3'-trichloro-biphenyl 
• 38444-88-1 3,4',5-trichlorobiphenyl 
• 475653-03-3 3-(3,5-dichlorophenyl)cyclopentanone 
• 351865-83-3 2-(3,5-dichlorophenyl)ethynyl-trimethylsilane 
• 67492-50-6 (3,5-dichlorophenyl)boronic acid 
• 33284-52-5 3,5,3',5'-tetrachlorobiphenyl 
• 179894-85-0 6-(3,5-Dichlorophenyl)-1,2-dihydro-2,2,4-trimethylquinoline 
• 108-70-3 1,3,5-trichlorobenzene 
• 1369431-36-6 3-(3,5-dichlorophenyl)-9-phenyl-9H-carbazole 
• 626-43-7 3,5-Dichloroaniline 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 3,5-DICHLORO-2,2,2-TRIFLUOROACETOPHENONE

The present invention relates to an improved process for the preparation of 3,5-Dichloro-2,2,2-Trifluoroacetophenone of formula (I). The present invention further provides an improved process for the preparation of Fluralaner using 3,5-dichloro-2,2,2-trifluoroacetophenone of formula (I) obtained by a process described herein.

Highly efficient Sandmeyer reaction on immobilized CuI/CuII-based catalysts

Highly effective embodiment of Sandmeyer reaction has been revealed for Cu-based catalysts incorporating ionic liquid on Silochrom support. The most active catalyst (TOF = = 4000–8000 h–1) contains comparable amounts of cuprous and cupric chloride anions. The reported method allows one to carry out the reaction for anilines in the one-pot mode.

Aromatic allylation via diazotization: Metal-free C-C bond formation

A new method for the synthesis of allyl aromatic compounds not involving any metal-containing reagent or catalyst has been developed. Arylamines substituted with a large number of different substituents were converted via diazotizative deamination with tert-butyl nitrite in allyl bromide and acetonitrile to the corresponding allyl aromatic compounds. The allylation reaction was found to be suitable for larger scale synthesis due to short reaction times, a nonextractive workup, and robustness toward moisture, air, and type of solvent.