1984-59-4

Basic information

• Product Name: 2,3-DICHLOROANISOLE
• Synonyms: 1,2-DICHLORO-3-METHOXYBENZENE;2,3-DICHLOROMETHOXYBENZENE;2,3-DICHLOROANISOLE;2,3-DICHLORANISOL;DICHLOROANISOLE(2,3-);1,2-dichloro-3-methoxy-benzen;ATRAZIN-2-HYDROXY PESTANAL, 250 MG;2,3-DICHLOROANISOLE, 97+%
• CAS NO: 1984-59-4
• Molecular Formula: C₇H₆Cl₂O
• Molecular Weight: 177.03
• EINECS: 217-853-1
• Product Categories: Aromatic Ethers;Anisole;Anisoles, Alkyloxy Compounds & Phenylacetates;Chlorine Compounds;Halogenated benzene series;Aromatics, Metabolites and Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1984-59-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 31-33 °C(lit.)
• Boiling Point: 115-116°C 12mm
• Flash Point: >230 °F
• Appearance: /
• Density: 1.2970 (rough estimate)
• Vapor Pressure: 0.144mmHg at 25°C
• Refractive Index: 1.5430 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform, Methanol
• Water Solubility: Soluble in water (86.9 mg/L).
• BRN: 1909166
• CAS DataBase Reference: 2,3-DICHLOROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DICHLOROANISOLE(1984-59-4)
• EPA Substance Registry System: 2,3-DICHLOROANISOLE(1984-59-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/22
• Safety Statements: 22-24/25-37/39-26
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 1984-59-4(Hazardous Substances Data)

Usage

Chemical Properties

white to brownish crystalline low melting solid

Uses

2,3-Dichloroanisole is a metabolite of pentachlorophenol (P238100) with fungicidal activity. 2,3-Dichloroanisole aling with other found in marine sediments.

InChI:InChI=1/C7H6Cl2O/c1-10-6-4-2-3-5(8)7(6)9/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 87-61-6 1,2,3-trichlorobenzene 
• 95-50-1 1,2-dichloro-benzene 
• 576-24-9 2,3-dichlorophenol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 92285-26-2 (2,3-dichloro-4-methoxyphenyl)(4-nitrophenyl)methanone 
• 2977-53-9 1-(2,3-dichloro-4-hydroxyphenyl)ethan-1-one 
• 213916-15-5 1-(bromomethyl)-2,3-dichloro-4-methoxybenzene 
• 62967-09-3 2,3-dichloro-4-methoxy-4'-fluorobenzophenone 
• 78697-41-3 2,3-dichloro-4-(4-hydroxybenzoyl)phenol 
• 57296-58-9 2,3-dichloro-5-phenylacetylanisole 
• 135055-88-8 (2-chloro-6-methoxy)diphenylamine 
• 2977-54-0 2-(4-acetyl-2,3-dichlorophenoxy)acetic acid 
• 92285-23-9 (2,3-dichloro-4-methoxyphenyl)(4-methoxyphenyl)-methanone 
• 93135-01-4 2,3-dichloro-4-<(4-nitrophenyl)acetyl>anisole 
• 72498-53-4 2,3-Dichloro-2'-fluoro-4-methoxybenzophenone 
• 23228-15-1 2,3-dichloro-4-(3-chloropropionyl)phenol 
• 93134-89-5 2,3-dichloro-4-<(4-methoxyphenyl)sulfonyl>anisole 
• 41715-70-2 2,3-dichloro-4'-methoxybutyrophenone 

Relevant articles and documents

A two-aromatic substituted propylene ketone compound and its preparation method and application (by machine translation)

The present invention discloses a two-aromatic substituted propylene ketone compound and its preparation method and application, its structural formula such as formula (I) as shown: Wherein A is B is hydrogen, methyl or ethyl; C is a substituted benzene ring, pyridine and furan heterocyclic, 2 - pyridyl, 3 - pyridyl, 4 - pyridyl, 5 - 1 H - indolyl, 4 - (N, N - dimethylamino) phenyl, 4 - (N - pyrrolyl) phenyl, 4 - [1 - (N - methyl piperazinyl)] phenyl or 4 - (1 - morpholinyl) phenyl. The compounds of the invention has a novel structure, to inhibit the cells MCL active effect, high safety, the preparation cost is low and the like, can be used as a MCL very promising drug. (by machine translation)

Benzene C-H Etherification via Photocatalytic Hydrogen-Evolution Cross-Coupling Reaction

Aryl ethers can be constructed from the direct coupling between the benzene C-H bond and the alcohol O-H bond with the evolution of hydrogen via the synergistic merger of photocatalysis and cobalt catalysis. Utilizing the dual catalyst system consisting of 3-cyano-1-methylquinolinum photocatalyst and cobaloxime, intermolecular etherification of arenes with various alcohols and intramolecular alkoxylation of 3-phenylpropanols with formation of chromanes are accomplished. These reactions proceed at remarkably mild conditions, and the sole byproduct is equivalent hydrogen gas.

THE REACTIONS OF UNACTIVATED ARYL HALIDES WITH SODIUM METHOXIDE IN HMPA; SYNTHESIS OF PHENOLS, ANISOLES, AND METHOXYPHENOLS

Sodium methoxide reacts with dichlorobenzenes in HMPA to give the chloroanisoles as a result of a SNAr process.Excess MeONa then effects the demethylation of the ethers to give the chlorophenols via an SN2 reaction.With tri- and tetrachlorobenzenes the initially formed chloroanisoles can be dealkylated to chlorophenols or can suffer further substitution to give the chlorodimethoxybenzenes; these react with excess MeONa to give the chloromethoxyphenols.The results obtained with the various isomers of the di-, tri-, and tetrachlorobenzenes are presented and discussed on the basis of the electronic effects of the substituents.