19865-33-9

Basic information

• Product Name: Propane, 1-(1-chloroethoxy)-2-methyl-
• Synonyms: 1-chloroethyl isobutyl ether;1-chloro-1-isobutoxy-ethane;1-Chlor-1-isobutoxy-aethan
• CAS NO: 19865-33-9
• Molecular Formula: C6H13ClO
• Molecular Weight: 136.622
• Mol File: 19865-33-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propane, 1-(1-chloroethoxy)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propane, 1-(1-chloroethoxy)-2-methyl-(19865-33-9)
• EPA Substance Registry System: Propane, 1-(1-chloroethoxy)-2-methyl-(19865-33-9)

Safety Data

• Hazardous Substances Data: 19865-33-9(Hazardous Substances Data)

Upstream product

• 109-53-5 isobutyl vinyl ether 
• 98-88-4 benzoyl chloride 

Downstream Products

• 109-53-5 isobutyl vinyl ether 

Relevant articles and documents

Cobalt(II)chloride catalysed cleavage of ethers with acyl halides: Scope and mechanism

Cobalt(II) chloride in acetonitrile catalyses the cleavage of a wide variety of ethers with acyl halides under mild conditions to give the corresponding esters in good yields. Acyclic aliphatic ethers are cleaved to the corresponding ester and chlorides whereas the cyclic aliphatic ethers give rise to the ω-chloroesters. The benzyl ethers can be converted to the corresponding esters along with the formation of benzyl chloride and benzyl acetamide. A comparative study for the cleavage of allyl and benzyl ether has revealed that benzyl ether can be selectively cleaved in presence of the allyl ethers. The oxiranes can be cleaved in highly regioselective manner to the corresponding-β-chloroesters. The vinyl ethers undergo sp2-hybridised carbon-oxygen bond cleavage under these conditions. Based on product analysis, a mechanism involving electron transfer followed by O-acylation and S(N)1 or S(N)2 attack by chloride-ion is discussed.