198821-79-3

Basic information

• Product Name: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE
• Synonyms: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE;BenzenaMine, 3-Methoxy-4-(5-oxazolyl)-;3-Methoxy-4-(oxazol-5-yl)aniline;3-Methoxy-4-(5-oxazolyl)aniline, 97%;3-Methoxy-4-(oxazol-5-yl)
• CAS NO: 198821-79-3
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.2
• Mol File: 198821-79-3.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 318.7±27.0 °C(Predicted)
• Appearance: /
• Density: 1.211±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.03±0.10(Predicted)
• CAS DataBase Reference: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE(198821-79-3)
• EPA Substance Registry System: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE(198821-79-3)

Safety Data

• Hazardous Substances Data: 198821-79-3(Hazardous Substances Data)

Usage

General Description

The chemical 3-Methoxy-4-(1,3-oxazol-5-yl)aniline, also known as MOA, is an organic compound with a molecular formula C10H10N2O2. It is commonly used in the manufacturing of pharmaceuticals and dyes, and has various applications in the chemical industry. It is a pale yellow crystalline solid with a melting point of 112-115°C, and is soluble in organic solvents such as ethanol and ether. 3-Methoxy-4-(1,3-oxazol-5-yl)aniline is known for its chemical reactivity and is used as a building block for the synthesis of various other organic compounds. It is important for researchers to handle this chemical with care, as it may pose health hazards upon exposure.

Upstream product

• 198821-77-1 (2-methoxy-4-nitrophenyl)methylene diacetate 
• 136507-15-8 4-nitro-2-methoxybenzaldehyde 
• 13120-77-9 2-methyl-5-nitroanisole 
• 198821-78-2 5-(2-methoxy-4-nitrophenyl)-oxazole 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 

Downstream Products

• 267647-77-8 C₁₈H₁₄N₄O₃ 
• 441756-44-1 N-(3-Cyanophenyl)-N'-[3-methoxy-4-(5-oxazolyl)phenyl]urea 
• 65-85-0 benzoic acid 
• 198821-22-6 VX-497 
• 1109236-67-0 C₁₈H₂₃N₃O₅ 

Relevant articles and documents

Optimization of a hydrogenation process using real-time mid-IR, heat flow and gas uptake measurements

This paper describes using real-time mid-IR, heat flow, and gas uptake data to optimize the hydrogenation of a nitroaromatic to an aniline that had been difficult to control during a previous campaign in the pilot plant. A bimetallic Pt/V catalyst was identified that eliminated the buildup of reaction intermediates and consequently resulted in an inherently more controllable process. The real-time analytics were then used to rapidly optimize the reaction conditions and develop strategies for controlling the reaction rate in the plant should an unexpected deviation occur.

NEW COMPOUNDS AND THEIR USE AS THERAPEUTICALLY ACTIVE SUBSTANCES IN THE TREATMENT AND/OR PREVENTION OF DISEASES INVOLVING THE RETINAL PIGMENT EPITHELIUM

The present invention relates to new compounds and to their use as therapeutically active substances in the treatment and/or prevention of diseases involving the retinal pigment epithelium, and in particular in the treatment and/or prevention of diseases

ARYL AMIDE KINASE INHIBITORS

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.