1989-32-8Relevant articles and documents
Diastereoselective synthesis of nicotine derivatives via 1,3-dipolar cycloaddition reactions
Ghandi, Mehdi,Taheri, Abuzar,Abbasi, Alireza
, p. 611 - 615 (2010)
(Chemical Equation Presented) A simple diastereoselective route to nicotine derivatives is presented. The one-pot three component 1,3-dipolar cycloaddition reaction of the Knoeevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived in situ from pyridine-3- carbaldehyde and sarcosine give access to nicotine derivatives in good yields.
Determination of thermodynamic affinities of various polar olefins as hydride, hydrogen atom, and electron acceptors in acetonitrile
Cao, Ying,Zhang, Song-Chen,Zhang, Min,Shen, Guang-Bin,Zhu, Xiao-Qing
, p. 7154 - 7168 (2013/08/23)
A series of 69 polar olefins with various typical structures (X) were synthesized and the thermodynamic affinities (defined in terms of the molar enthalpy changes or the standard redox potentials in this work) of the polar olefins obtaining hydride anions, hydrogen atoms, and electrons, the thermodynamic affinities of the radical anions of the polar olefins (X ?-) obtaining protons and hydrogen atoms, and the thermodynamic affinities of the hydrogen adducts of the polar olefins (XH?) obtaining electrons in acetonitrile were determined using titration calorimetry and electrochemical methods. The pure Ci - 'C π-bond heterolytic and homolytic dissociation energies of the polar olefins (X) in acetonitrile and the pure Ci - 'C π-bond homolytic dissociation energies of the radical anions of the polar olefins (X?-) in acetonitrile were estimated. The remote substituent effects on the six thermodynamic affinities of the polar olefins and their related reaction intermediates were examined using the Hammett linear free-energy relationships; the results show that the Hammett linear free-energy relationships all hold in the six chemical and electrochemical processes. The information disclosed in this work could not only supply a gap of the chemical thermodynamics of olefins as one class of very important organic unsaturated compounds but also strongly promote the fast development of the chemistry and applications of olefins.
Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles
Mandha, Santhosh Reddy,Siliveri, Sravanthi,Alla, Manjula,Bommena, Vittal Rao,Bommineni, Madhava Reddy,Balasubramanian, Sridhar
supporting information; experimental part, p. 5272 - 5278 (2012/09/07)
An ecofriendly green approach for synthesis of substituted pyrano[2,3-c]pyrazoles has been developed via a multicomponent one pot approach in aqueous ethanol medium under totally non-catalytic conditions. The synthesized compounds were evaluated for their
