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199188-97-1

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199188-97-1 Usage

General Description

(3RS)-N-Methyl-3-phenyl-3-[2-(trifluoroMethyl)-phenoxy]propan-1-aMine Hydrochloride, also known as the 2-TrifluoroMethylisoMer of Fluoxetine Hydro-chloride, is a chemical compound with potential pharmacological activities. It is a derivative of the antidepressant drug fluoxetine, and is proposed to have similar effects in the treatment of mood disorders and anxiety. The compound is a selective serotonin reuptake inhibitor (SSRI), meaning it works by increasing the levels of serotonin in the brain, which can help to regulate mood and reduce symptoms of depression. Additionally, as a trifluoromethyl derivative, it may also have enhanced potency and improved pharmacokinetic properties compared to the original compound. Further research on this chemical may reveal its potential as a novel antidepressant or anxiolytic medication.

Check Digit Verification of cas no

The CAS Registry Mumber 199188-97-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,1,8 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 199188-97:
(8*1)+(7*9)+(6*9)+(5*1)+(4*8)+(3*8)+(2*9)+(1*7)=211
211 % 10 = 1
So 199188-97-1 is a valid CAS Registry Number.

199188-97-1Downstream Products

199188-97-1Relevant articles and documents

Copper catalyzed: N-formylation of α-silyl-substituted tertiary N-alkylamines by air

Bruce, Lachlan David,Chan, Philip Wai Hong,Jin, Jianwen,Xia, Bo,Zhao, Yichao

supporting information, p. 5296 - 5302 (2020/09/17)

A site-selective method to prepare N-formyl amines efficiently that relies on the copper(i)-catalyzed oxidation of α-silyl-substituted tertiary N-alkylamines by air at room temperature is described. The oxidative protocol was shown to exhibit excellent functional group tolerance as it was applicable to a wide variety of amine substrates and a number of bioactive molecules and natural products. Moreover, it delinates a ligand-and additive-free amine oxidation process mediated by a low-cost metal salt with oxygen from air taking on the role of both the terminal oxidant and as part of the formylation reagent, which is unprecedented in copper catalysis. It also offers the first synthetic method that can selectively generate α-amino radical species as reactive intermediates from α-silylamines under non-photochemical reaction conditions.

Method for preparing formamide derivative by using catalyst-free transamination reaction

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Paragraph 0050; 0051, (2019/02/13)

The invention discloses a method for synthesizing a formamide derivative by using a low-reactive catalyst-free and solvent-free tertiary amide and aliphatic amine transamination reaction, wherein thehigh-yield formamide derivative is obtained by directly using N,N-dimethylformamide (DMF) as a formyl source. According to the present invention, the method has advantages of inexpensive and easily available raw materials, inexpensive and easily available acylating reagent, high reaction yield, one-step reaction, low cost, high reaction selectivity, simple operation and the like, and can overcomethe defects of high toxicity of the reaction reagent, requirement of different types of catalysts, high cost, more reaction steps, more by-products and the like in the prior art.

Method for synthesizing formamide derivatives by molybdenum catalyzed formylation reaction

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Paragraph 0065; 0066, (2018/05/16)

The invention discloses a method for synthesizing formamide derivatives by molybdenum catalyzed formylation reaction. The method includes that the formamide derivatives are generated by one-pot reaction of amine compounds and formamide compounds under the catalytic action of molybdenum salts and/or molybdenum oxides. Reaction methods and catalysts are cheap and easy to acquire, reaction steps andoperations are simple, the method has advantages of high reaction selectivity, high yield, expandability in reaction and the like, and defects of high toxicity of reaction agents, expensive catalysts,complex reaction steps, high quality of by-products and the like in the prior art are overcome.

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