19920-84-4

Basic information

• Product Name: 1-Bromo-3-cyclohexylbenzene
• Synonyms: 1-Bromo-3-cyclohexylbenzene
• CAS NO: 19920-84-4
• Molecular Formula: C₁₂H₁₅Br
• Molecular Weight: 239.1515
• Mol File: 19920-84-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 289.2±19.0 °C(Predicted)
• Appearance: /
• Density: 1.280±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Bromo-3-cyclohexylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-3-cyclohexylbenzene(19920-84-4)
• EPA Substance Registry System: 1-Bromo-3-cyclohexylbenzene(19920-84-4)

Safety Data

• Hazardous Substances Data: 19920-84-4(Hazardous Substances Data)

Usage

General Description

1-Bromo-3-cyclohexylbenzene is a chemical compound with the formula C12H15Br. It is a colorless liquid with a molecular weight of 243.15 g/mol. 1-Bromo-3-cyclohexylbenzene is an aryl halide, specifically a brominated derivative of cyclohexylbenzene. It is used as a building block in the synthesis of various organic compounds and can participate in a wide range of chemical reactions, including nucleophilic substitution and palladium-catalyzed cross-coupling reactions. Its unique structure and reactivity make it a valuable tool in organic synthesis and medicinal chemistry. However, it is important to handle 1-Bromo-3-cyclohexylbenzene with caution, as it is a potential irritant and can be harmful if inhaled, ingested, or comes into contact with the skin.

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Downstream Products

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Relevant articles and documents

Modular Generation of (Iodinated) Polyarenes Using Triethylgermane as Orthogonal Masking Group

While the modular construction of molecules from suitable building blocks is a powerful means to more rapidly generate a diversity of molecules than through customized syntheses, the further evolution of the underlying coupling methodology is key to realize widespread applications. We herein disclose a complementary modular coupling approach to the widely employed Suzuki coupling strategy of boron containing precursors, which relies on organogermane containing building blocks as key orthogonal functionality and an electrophilic (rather than nucleophilic) unmasking event paired with air-stable PdI dimer based bond construction. This allows to significantly shorten the reaction times for the iterative coupling steps and/or to close gaps in the accessible compound space, enabling straightforward access also to iodinated compounds.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.