199341-50-9

Basic information

• Product Name: ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid
• Synonyms: ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid
• CAS NO: 199341-50-9
• Molecular Weight: 218.163
• Mol File: 199341-50-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid(199341-50-9)
• EPA Substance Registry System: ((S)-4-Methoxycarbonylmethyl-5-oxo-[1,3]dioxolan-4-yl)-acetic acid(199341-50-9)

Safety Data

• Hazardous Substances Data: 199341-50-9(Hazardous Substances Data)

Upstream product

• 77-92-9 citric acid 
• 4767-12-8 4,4-(5-oxo-1,3-dioxolane)diacetic acid anhydride 
• 144-16-1 5-oxo-1,3-dioxolan-4-ylidenedi(acetic acid) 
• 77862-72-7 (5-oxo-[1,3]dioxolane-4,4-diyl)-bis-acetic acid dimethyl ester 
• 184834-31-9 [-(2-methoxy-2-oxoethyl)-5-oxo-1,3-dioxolan-4-yl]acetic acid 

Downstream Products

• 77-93-0 citric acid triethyl ester 

Relevant articles and documents

Regio- and enantioselectivity of the enzyme-catalyzed hydrolysis of citric acid derivatives

The hydrolysis of triethyl citrate in the presence of three serine proteases (chymotrypsin, subtilisin BPN', subtilisin carlsberg) is highly regioselective and gives the symmetric diester. Several lipases and proteases have the complementary regioselectivity and give the chiral diester. Pig liver esterase, Aspergillus niger lipase and Candida antarctica lipase give the chiral (R)-diester with good regio- and enantioselectivity. The stereoselective hydrolysis of the meso citric derivatives 7a,b in the presence of Candida antarctica lipase gives the corresponding (R)-monoester.