199987-17-2 Usage
Bicyclic aromatic compound
Indenone derivative The compound is based on a bicyclic (two-ring) structure with aromatic properties, derived from indenone.
Methoxy groups present
5-methoxy and 2-(4-methoxyphenyl) Two methoxy groups (-OCH3) are attached to the compound, one on the 5th carbon of the indenone ring and another on the 4th carbon of the methoxyphenyl group.
Methoxyphenyl group attachment
2-(4-methoxyphenyl) A methoxyphenyl group is attached to the 2nd carbon of the indenone ring, which contributes to the compound's unique structure.
Potential applications
Pharmaceutical and medicinal chemistry Due to its unique structure and potential biological activities, the compound may have applications in the pharmaceutical and medicinal chemistry fields.
Check Digit Verification of cas no
The CAS Registry Mumber 199987-17-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,9,8 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 199987-17:
(8*1)+(7*9)+(6*9)+(5*9)+(4*8)+(3*7)+(2*1)+(1*7)=232
232 % 10 = 2
So 199987-17-2 is a valid CAS Registry Number.
199987-17-2Relevant articles and documents
Enolate Ions as ss-Activators of ortho-metalation: Direct Synthesis of 3-Aminoindenones
Kayaleh, Nadim E.,Gupta, Ramesh C.,Johnson, Francis
, p. 4515 - 4522 (2007/10/03)
ss-Ketonitriles derived from a Claisen condensation of benzoate esters with alkyl- or phenylacetonitriles lead to 3-aminoindenones in the presence of excess LDA. This new reaction is also applicable to pyridine carboxylic esters. All of the 3-aminoindenones and their aza analogues can be hydrolyzed by acid to give the corresponding 1,3-indandiones. The mechanism of the reaction falls into the directed-ortho-metalation class in which the initial enolate ion of the keto-nitrile directs self-metalation at an ortho position. The new anion then cyclizes onto the nitrile group to generate an aminoindenone. Surprisingly the simplest member of the series, benzoylacetonitrile, does not undergo cyclization. Mechanistic isotope studies revealed that this substance preferentially and directly forms a dianion on the side chain, which is not further deprotonated at the ortho position of the aromatic ring.
