200418-23-1Relevant articles and documents
Design, synthesis, and preliminary pharmacological evaluation of 1,4- diazabicyclo[4.3.0]nonan-9-ones as a new class of highly potent nootropic agents
Manetti, Dina,Ghelardini, Carla,Bartolini, Alessandro,Bellucci, Cristina,Dei, Silvia,Galeotti, Nicoletta,Gualtieri, Fulvio,Romanelli, Maria Novella,Scapecchi, Serena,Teodori, Elisabetta
, p. 1969 - 1974 (2007/10/03)
Several 4-substituted 1,4-diazabicyclo[4.3.0]nonan-9-ones have been synthesized and tested in vivo on mouse passive avoidance test, to evaluate their nootropic activity. The results show that they represent a new class of nootropic drugs with a pharmacolo