2007-97-8

Basic information

• Product Name: CATECHYLPHOSPHOROTRICHLORIDE
• Synonyms: 1,2-PHENYLENE PHOSPHOROTRICHLORIDITE;CATECHYLPHOSPHOROTRICHLORIDE;1,3,2-Benzodioxaphosphole,2,2,2-trichloro-2,2-dihydro-;Catechyl phosphorus trichloride~2,2,2-Trichloro-1,3,2-benzodioxaphosphole;2,2,2-trichloro-1,3,2-benzodioxaphosphole;catechyl phosphorus trichloride;8,8,8-trichloro-7,9-dioxa-8$l^{5}-phosphabicyclo[4.3.0]nona-1,3,5-triene;2,2,2-Trichloro-2lambda5-benzo[d][1,3,2]dioxaphosphole
• CAS NO: 2007-97-8
• Molecular Formula: C₆H₄Cl₃O₂P
• Molecular Weight: 245.43
• EINECS: 217-913-7
• Mol File: 2007-97-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 48-50°C
• Boiling Point: 102-104°C 2mm
• Flash Point: 102-104°C/2mm
• Appearance: /
• Sensitive: Moisture Sensitive
• BRN: 743959
• CAS DataBase Reference: CATECHYLPHOSPHOROTRICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CATECHYLPHOSPHOROTRICHLORIDE(2007-97-8)
• EPA Substance Registry System: CATECHYLPHOSPHOROTRICHLORIDE(2007-97-8)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3261
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 2007-97-8(Hazardous Substances Data)

Usage

General Description

Catechylphosphorotrichloride, also known as CPCT, is a chemical compound commonly used as a reagent in organic synthesis. It is an important intermediate in the production of various phosphorus-containing compounds, including phosphonates and phosphoramidates. CPCT is used in the pharmaceutical industry for the synthesis of antiviral and antitumor agents, as well as in the production of insecticides and herbicides. It is a highly reactive and corrosive compound, and must be handled with caution due to its toxic and irritating properties. CPCT is also a widely used reagent in the preparation of phosphorus-containing polymers and materials for industrial and research applications.

InChI:InChI=1/C6H4Cl3O2P/c7-12(8,9)10-5-3-1-2-4-6(5)11-12/h1-4H

Upstream product

• 1641-40-3 pyrocatechol phosphorochloridite 
• 120-80-9 benzene-1,2-diol 
• 10026-13-8 phosphorus pentachloride 
• 71-43-2 benzene 
• 137018-66-7 dichloro(2-methoxyphenoxy)phosphine 

Downstream Products

• 130304-82-4 2-Chloro-2-(2,2-dichloro-2-phenyl-ethylidene)-2λ⁵-benzo[1,3,2]dioxaphosphole 
• 19579-02-3 2-phenoxy-2,2'-spirobi<1,3,2λ⁵-benzodioxaphosphole> 
• 96-18-4 1,2,3-trichloropropane 
• 618-34-8 1-chlorostyrene 
• 193554-93-7 2,6-dichloro-2-oxo-4-phenylbenzo[e]-1,2λ⁵-oxaphosphorin-3-ene 
• 223480-14-6 2-chloro-4-(4-chlorophenyl)-2H-(4-chlorobenzo)[e][1,2]oxaphosphorin-3-ene 2-oxide 
• 7647-01-0 hydrogenchloride 
• 1499-17-8 o-phenylene chlorophosphate 
• 15719-64-9 methylammonium carbonate 
• 1641-40-3 pyrocatechol phosphorochloridite 
• 94839-48-2 4-Chloro-5-methyl-2-phenyl-2H-1,2,3-diazaphosphol 
• 74582-23-3 3-chloro-5-methyl-2-phenyl-1,2,3-diazaphosphol-1-ene 
• 371160-19-9 2,7-dichloro-4-phenyl-benzo[e][1,2]oxaphosphinine 2-oxide 
• 130304-83-5 2-(2,2-Dichloro-2-phenyl-ethylidene)-2-fluoro-2λ⁵-benzo[1,3,2]dioxaphosphole 

Relevant articles and documents

Synthesis of racemic P-chiral phosphine oxides and phosphonium salts by stepwise reaction of phosphacoumarins with organomagnesium compounds

A new effective synthetic route to the racemic phosphine oxides and phosphonium salts with a P-asymmetric center was developed based on the stepwise reaction of phosphacoumarins with organomagnesium compounds. A selective P–C bond formation was achieved on each step owing to the differences in reactivity of the exocyclic P–Cl or P–O bonds and endocyclic P–O bond of phosphacoumarins. It was found that the P(O)OMgX fragment of the phosphocoumarin salt does not hinder in the substitution reaction at the phosphorus atom accompanied by ring-opening and P–C bond formation.

SYNTHESIS AND PROPERTIES OF 2-HEXAFLUOROISOPROPOXY-1,3,2λ5-BENZODIOXAPHOSPHOLANE 2,2-DIHALIDES

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CHLORIERUNG VON o-METHOXYPHENYL-DICHLORPHOSPHIT-EINE LITERATURKORREKTUR

o-Methoxyphenyl dichlorophosphit 1 reacts with chlorine to give o-phenylenedioxy-trichlorophosporane 4 and with antimony pentachloride to give o-methoxyphenoxy-trichlorophosphonium-hexachloroantimonate. o-Methoxyphenoxy-tetrachlorophosphorane 2 cannot be isolated. Key words: Dioxytrichlorophosphorane; aryl-oxy-trichlorophosphonium salt; cyclisation.