20075-26-7Relevant articles and documents
Assembly of the active center of organophosphorus hydrolase in metal-organic frameworks: Via rational combination of functional ligands
Xia, Mengfan,Zhuo, Caixia,Ma, Xuejuan,Zhang, Xiaohong,Sun, Huaming,Zhai, Quanguo,Zhang, Yaodong
, p. 11302 - 11305 (2017)
Different from popular mimics of bimetallic nuclear centers bridged by a hydroxide, a total coordination sphere of the active center of organophosphorus hydrolase was assembled in metal-organic frameworks by rational design and combination of ligands, which resulted in efficient destruction of nerve agent stimulants without a base as a co-catalyst.
BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES
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Page/Page column 142-143, (2009/12/23)
The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.
Arylsulfonamidobenzylic compounds
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Page 20, (2010/02/05)
Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases.