20127-62-2

Basic information

• Product Name: 9H-Pyrido[3,4-b]indole, 1-(2-phenylethenyl)-
• CAS NO: 20127-62-2
• Molecular Formula: C19H14N2
• Molecular Weight: 270.334
• Mol File: 20127-62-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 9H-Pyrido[3,4-b]indole, 1-(2-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Pyrido[3,4-b]indole, 1-(2-phenylethenyl)-(20127-62-2)
• EPA Substance Registry System: 9H-Pyrido[3,4-b]indole, 1-(2-phenylethenyl)-(20127-62-2)

Safety Data

• Hazardous Substances Data: 20127-62-2(Hazardous Substances Data)

Upstream product

• 486-84-0 harmane 
• 100-52-7 benzaldehyde 
• 54-12-6 Trp 
• 522-87-2 yohimbinic acid 
• 61-54-1 tryptamine 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Downstream Products

• 154105-63-2 9-(4-Methoxy-benzyl)-9H-β-carboline-1-carbaldehyde 
• 31482-18-5 pauridianthine 
• 154105-70-1 9-[1-(4-Bromo-pyridin-3-yl)-ethyl]-1-((E)-styryl)-9H-β-carboline 
• 154105-62-1 9-(4-Methoxy-benzyl)-1-((E)-styryl)-9H-β-carboline 

Relevant articles and documents

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Green synthesis method for beta-carboline heterocyclic compounds

The invention discloses a green synthesis method for beta-carboline heterocyclic compounds. The green synthesis method includes that the beta-carboline heterocyclic compounds are made of alcohols compounds, oxidative condensation, cyclization and re-oxidation one-pot cascade reaction is carried out on tryptamines compounds and alcohol in oxygen under the catalytic effects of catalysts TEMPO and catalysts TBN to obtain the beta-carboline heterocyclic compounds, the reaction temperatures range from 40 DEG C to 120 DEG C, and the reaction time ranges from 6 hours to 48 hours. The green synthesismethod has the advantages that inexpensive, easily available, stable and low-toxicity alcohols which can come from wide sources are used as the raw materials for the beta-carboline heterocyclic compounds, the aerobic oxidative condensation, cyclization and re-oxidation cascade reaction is carried out on the tryptamines compounds and the alcohol under the synergistic catalytic effects of the catalysts TEMPO and the catalysts TBN and acetic acid solvent conditions to prepare the beta-carboline heterocyclic compounds, target products are high in selectivity, a byproduct is water, and accordinglythe green synthesis method is high in efficiency and free of pollution.

Inhibitors of cyclic AMP phosphodiesterase in Picrasma quassioides Bennet, and inhibitory activities of related β-carboline alkaloids

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