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2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile

    Cas No: 201424-86-4

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  • 201424-86-4 Structure
  • Basic information

    1. Product Name: 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
    2. Synonyms: 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
    3. CAS NO:201424-86-4
    4. Molecular Formula: C14H18N2O2
    5. Molecular Weight: 246.30492
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 201424-86-4.mol
  • Chemical Properties

    1. Melting Point: 174-176 °C(Solv: ethanol (64-17-5))
    2. Boiling Point: 454.7±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.17±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.46±0.60(Predicted)
    10. CAS DataBase Reference: 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(201424-86-4)
    12. EPA Substance Registry System: 2-amino-4-ethyl-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile(201424-86-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 201424-86-4(Hazardous Substances Data)

201424-86-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 201424-86-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,4,2 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 201424-86:
(8*2)+(7*0)+(6*1)+(5*4)+(4*2)+(3*4)+(2*8)+(1*6)=84
84 % 10 = 4
So 201424-86-4 is a valid CAS Registry Number.

201424-86-4Downstream Products

201424-86-4Relevant articles and documents

Catalyst-free green synthesis of tetrahydro-benzo[b]pyrans in magnetized water: experimental aspects and molecular dynamics simulation

Bakherad, Mohammad,Moosavi, Fatemeh,Keivanloo, Ali,Doosti, Rahele,Moradian, Elmira,Armaghan, Mahsa

, p. 2981 - 2997 (2019/02/28)

In this work, magnetized water is applied as a green-promoting medium for the catalyst-free, one-pot, practical, efficient, and environmentally benign multi-component synthesis of tetrahydrobenzo[b]pyrans. Some tetrahydrobenzo[b]pyran derivatives are synt

Prolinamide functionalized polyacrylonitrile fiber with tunable linker length and surface microenvironment as efficient catalyst for Knoevenagel condensation and related multicomponent tandem reactions

Zhu, Hai,Xu, Gang,Du, Huimin,Zhang, Chenlu,Ma, Ning,Zhang, Wenqin

, p. 217 - 229 (2019/05/16)

A series of new prolinamide polyacrylonitrile fiber catalysts with tunable length of alkyl linker and different linker group were prepared by covalent bonding for the first time and well characterized by mechanical strength, FT-IR, XRD, EA, TGA, SEM and water contact angel. The catalytic activities of these fiber catalysts were evaluated in Knoevenagel condensation and one-pot Knoevenagel-Michael multicomponent tandem reactions to synthesize α, β-unsaturated nitrile and 2-amino-4H-chromene derivatives in water. The result show that the suitable linker length attaching amines to fiber matrix as well as the constructed hydrophobic microenvironment by linker group within the surface layers of fiber materials effectively promotes the reactions. In addition, the good swollen capacity of fiber in solvent ensure that the reaction proceed well. Fiber catalyst PANPA?2F modified by prolinamide with a C2 alkyl chain exhibited the best catalytic performance and can be easily recovered and reused for at least ten consecutive cycles without significant loss of catalytic activity and active sites leaching.

Synthesis, Characterization, and Catalytic Behavior of Bamboo Rice Husk Ash

Maheswari, Cinnathambi Subramani,Ramesh, Rathinam,Lalitha, Appaswami

, p. 889 - 895 (2017/09/01)

In this paper, we report the use of bamboo rice husk ash as an efficient, greener, reusable, and biodegradable heterogeneous catalyst for the synthesis of tetrahydro-4H-chromene-3-carbonitriles via the one-pot three-component reaction of malononitrile wit

Aqua-mediated multicomponent synthesis of various 4H-pyran derivatives catalyzed by poly(4-vinylpyridine)-supported copper iodide nanoparticle catalyst

Albadi, Jalal,Mansournezhad, Azam

, p. 5739 - 5752 (2016/06/01)

A green and efficient approach for synthesis of some new 4H-pyran derivatives is reported, catalyzed by green recyclable poly(4-vinylpyridine)-supported copper iodide nanoparticle catalyst in water. This procedure has many advantages such as operational s

Titanium dioxide nanoparticles as efficient catalyst for the synthesis of pyran’s annulated heterocyclic systems via three-component reaction

Edjlali, Ladan,Khanamiri, Rahim Hosseinzdeh

, p. 1221 - 1225 (2016/07/30)

Abstract: Titanium dioxide nanoparticles were introduced as a new and efficient heterogeneous catalyst for the synthesis of pyran’s annulated heterocyclic systems via three-component reaction. The reaction was carried out between various aldehydes, malononitrile, and cyclic CH-acids in H2O as a green solvent at 50?°C during 10?h. This reaction gave pyrans containing heterocyclic compounds including nineteen derivatives in good yields. Titanium dioxide nanoparticles were recycled and reused for six times without significant decrease in the catalyst amount and efficiency. This approach is very efficient, economical, and environmentally benign process since titanium dioxide is a cheap, available, non-toxic, and recyclable catalyst. Graphical Abstract: [Figure not available: see fulltext.]

Atom-economy click synthesis of tetrahydrobenzo[b]pyrans using carbon-based solid acid as a novel, highly efficient and reusable heterogeneous catalyst

Moghaddas, Maryam,Davoodnia, Abolghasem

, p. 4373 - 4386 (2015/06/30)

Carbon-based solid acid has been used as a mild and efficient heterogeneous catalyst for the synthesis of tetrahydrobenzo[b]pyran derivatives via a one-vessel, three-component cyclocondensation of dimedone, aryl aldehydes, and malononitrile with high atom

Green synthesis of 2-Amino-3-Cyano-4h-Chromenes in water using nano silica-Bonded 5-N-Propyl-Octahydro-Pyrimido[1,2-A]Azepinium chloride as an effective and reusable nano catalyst

Baharfar, Robabeh,Asghari, Sakineh,Shariati, Narges

, p. 2900 - 2904 (2015/11/03)

Nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) is reported as an highly efficient and recyclable nano catalyst for the preparation of 4H-chromene derivatives in aqueous media. This synthetic method offers a simple, mil

A facile and efficient synthesis of 2-amino-3-cyano-4H-chromenes and tetrahydrobenzo[b]pyrans using 2,2,2-trifluoroethanol as a metal-free and reusable medium

Khaksar, Samad,Rouhollahpour, Ahmad,Talesh, Saeed Mohammadzadeh

experimental part, p. 11 - 15 (2012/09/21)

A highly efficient one-pot three-component regioselective synthesis of 2-amino-3-cyano-4H-chromene and tetrahydrobenzo[b]pyran derivatives has been developed by annulation of aldehydes, malononitrile, and resorcinol or dimedone under reflux conditions in

Phenylboronic acid as an efficient and convenient catalyst for a three-component synthesis of tetrahydrobenzo[b]pyrans

Nemouchi, Sara,Boulcina, Raouf,Carboni, Bertrand,Debache, Abdelmadjid

experimental part, p. 394 - 397 (2012/07/27)

Phenylboronic acid, a non-toxic compound, is used as catalyst for an efficient, rapid, and one-pot three-component synthesis of tetrahydrobenzo[b] pyrans in good to excellent yields. This new procedure has the advantages of operational simplicity, shorter

A green one-pot multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications using silica nanoparticles as reusable catalyst

Banerjee, Subhash,Horn, Alissa,Khatri, Hari,Sereda, Grigoriy

supporting information; experimental part, p. 1878 - 1881 (2011/04/26)

A one-pot practical, efficient, and environmentally benign multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications has been developed using a very mild, neutral, and reusable s

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