202124-89-8

Basic information

• Product Name: 1H-Indole-3-aceticacid,5-cyano-(9CI)
• Synonyms: 1H-Indole-3-aceticacid,5-cyano-(9CI);5-cyano-1H-Indole-3-acetic acid;2-(5-Cyano-1H-indol-3-yl)acetic acid
• CAS NO: 202124-89-8
• Molecular Formula: C₁₁H₈N₂O₂
• Molecular Weight: 200.19342
• Product Categories: INDOLE
• Mol File: 202124-89-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole-3-aceticacid,5-cyano-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-aceticacid,5-cyano-(9CI)(202124-89-8)
• EPA Substance Registry System: 1H-Indole-3-aceticacid,5-cyano-(9CI)(202124-89-8)

Safety Data

• Hazardous Substances Data: 202124-89-8(Hazardous Substances Data)

Usage

Family

Indole-3-acetic acids

Type

Synthetic derivative

Parent Compound

Plant hormone indole-3-acetic acid

Role in plants

Regulation of plant growth and development

Additional functional group

Cyano group at the 5th position of the indole ring

Potential applications

Agriculture and horticultural practices

Research status

Further research needed to understand effects and potential uses

Upstream product

• 202124-88-7 methyl (5-cyano-1H-indol-3-yl)(oxo)acetate 
• 15861-24-2 1H-indole-5-carbonitrile 
• 202124-86-5 methyl (5-cyano-1H-indol-3-yl)acetate 

Downstream Products

• 316364-49-5 2-(5-cyano-1H-indol-3-yl)-N-(2'-propylsulfamoyl-biphenyl-4-yl)-acetamide 
• 316364-46-2 2-(5-cyano-1H-indol-3-yl)-N-(2'-ethylsulfamoyl-biphenyl-4-yl)-acetamide 
• 316364-45-1 2-(5-cyano-1H-indol-3-yl)-N-(2'-methylsulfamoyl-biphenyl-4-yl)-acetamide 
• 221290-11-5 2-(5-cyano-1H-indol-3-yl)-N-(2'-sulfamoyl-biphenyl-4-yl)-acetamide 
• 316364-43-9 2-(5-cyano-1H-indol-3-yl)-N-[5-(2-sulfamoyl-phenyl)-pyridin-2-yl]-acetamide 
• 316364-41-7 2-(5-cyano-1H-indol-3-yl)-N-methyl-N-(2'-sulfamoyl-biphenyl-4-yl)-acetamide 

Relevant articles and documents

A substituted indole -3 - acetic acid synthesis method (by machine translation)

The present invention provides a substituted indole - 3 - acetic acid synthesis method, comprises the following steps: (1) in order to replace the indole as the starting material, with the acylation reagent under the action of catalyst through the tutor - acylation to obtain the 1, 3 - diacetyl substituted indole; (2) intermediate 1, 3 - diacetyl substituted indole does not need refining, directly with the morpholine and sulfur by the Willgerodt - Kindler rearrangement reaction, the inorganic under the catalysis of alkali hydrolysis, acidified to obtain substituted indole - 3 - acetic acid. (by machine translation)

Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors

Thrombotic diseases are a major cause of death and morbidity. Factor Xa (fXa) plays a vital role in the regulation of normal homeostasis and abnormal intravascular thrombus development in the blood coagulation cascade. A novel series of fXa inhibitors inc