2028-84-4Relevant articles and documents
Ultrasound Assisted Synthesis of Some Novel Bis-Pyridazine Derivatives
Mekky, Ahmed E. M.,Al-Bogami, Abdullah S.
, p. 595 - 605 (2016)
Bis-enaminone 3 was coupled with aryldiazonium chlorides 4a, 4b to afford the bis-arylhydrazonopropanals 6a, 6b. Compounds 6a, 6b could be utilized for the synthesis of a variety of bis-(dimethyl 2,3-dihydropyridazine-3,4-dicarboxylate), bis-(pyridazin-3(
Novel method for the synthesis of 6,12-dihydro-2-methylindolo[2,3- b]carbazol-6-ones
Ebenezer Martin,Prasad, K. J. Rajendra
, p. 1778 - 1783 (2008)
A novel method for the synthesis of 6,12-dihydro-2-methylindolo[2,3-b] carbazol-6-ones was developed from 1-oxo-2,3,4,9-tetrahydro-1H-carbazol-1-one through methyl 6-methyl-2-(1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)oxoacetate in good yields. This metho
Synthesis and antioxidant assay of new nicotinonitrile analogues clubbed thiazole, pyrazole and/or pyridine ring systems
Abumelha, Hana M. A.
, (2020/01/21)
A series of novel nicotinonitrile derivatives were synthesized by hybridization with thiazole, pyrazole, and pyridine ring systems using 4-aminobenzohydrazide as link-bridge. The synthetic strategy of nicotinonitrile-thiazole analogues involves cyclizatio
New Thiophene Derivatives as Antimicrobial Agents
Mabkhot, Yahia Nasser,Kaal, Nahed Ahmed,Alterary, Seham,Mubarak, Mohammad S.,Alsayari, Abdulrhman,Bin Muhsinah, Abdullatif
, p. 2845 - 2953 (2019/08/26)
Phenacylbromide derivatives constitute a multilateral group of precursors for the synthesis of numerous heterocycles of organic compounds. Briefly, 5-(2-bromo-acetyl)-substituted-thiophene derivative has been used as a synthon for synthesis of new thiophene-containing compounds through the reaction with nucleophilic nitrogen compounds and thioamides. The suggested structures of the newly synthesized thiophene compounds were confirmed and assured with different spectroscopic tools and with CHN elemental analysis. Additionally, the antimicrobial activity of these thiophene compounds was recorded to investigate their potency against various types of bacteria and fungi. Results showed that these compounds exhibit significant inhibitory activity against the growth of tested bacterial and fungal strains and that some derivatives were more potent than the employed reference drugs.