2038-05-3Relevant articles and documents
A biomimetic electrocatalytic system for the atom-economical chemoselective synthesis of secondary amines
Largeron, Martine,Fleury
supporting information; experimental part, p. 883 - 886 (2009/07/25)
A facile one-pot oxidation-imine formation-reduction route to secondary amines can be achieved electrolytically from primary amines. This atom-economical 1ox-mediated sequence, leaving ammonia as the sole byproduct, allows the rapid chemoselect
A mild chemospecific reductive dehalogenation of ethylaminobenzamides with lithium aluminum hydride
Hendrix, James A.,Stefany, David W.
, p. 6749 - 6752 (2007/10/03)
A mild reduction of ortho-fluoro benzamides was discovered using LAH. The reaction proceeds cleanly and in moderate yields. The scope of the reaction is explored and a mechanism is proposed. A two carbon spacer between the amide and a 3°amine is optimal for this chelation controlled reaction.