205448-66-4Relevant articles and documents
MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF
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Paragraph 0254; 0259-0260, (2021/07/08)
The present invention relates to multi-substituted pyridone derivatives and therapeutic use thereof. In particular, the present invention relates to a compound of formula (I), a preparation method therefor, a pharmaceutical composition comprising the same, as well as use thereof as a tyrosine kinase inhibitor, in particular, use thereof in treating a disease associated with tyrosine kinase activity. Each substituent in the formula (I) is defined as in the specification.
NOVEL POLYMORPHS OF 4-[3-CHLORO-4-(N'-CYCLOPROPYL UREIDO)PHENOXY]-7-METHOXYQUINOLINE-6-CARBOXAMIDE, ITS SALTS AND PROCESS FOR THE PREPARATION THEREOF
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, (2019/06/23)
The present invention relates to novel polymorphs of 4-[3-chloro-4-(N'- cyclopropyl ureido) phenoxy]-7- methoxyquinoline- 6- carboxamide methanesulfonate represented by following structural formula-1a and process for preparation thereof. Further, the pres
Thiazolidone derivative of lovatinib acid and application of thiazolidone derivative
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Paragraph 0018-0020, (2019/11/21)
The invention discloses 4-[3-chlorine group-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinoline formyl thiazolone and application thereof. The structure conforms the general formula (I) (please see the specification of the formula), the effica