205526-22-3

Basic information

• Product Name: FMOC-D-2-Chlorophe
• Synonyms: RARECHEM BK PT 0006;(R)-3-(2-CHLORO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-CHLORO-D-PHENYLALANINE;FMOC-2-CHLORO-D-PHENYLALANINE;Fluorenylmethoxycarbonyl-D-2-chlorophenylalanine;FMOC-O-CHLORO-D-PHE-OH;FMOC-D-2-CHLOROPHE;FMOC-D-2-CHLOROPHENYLALANINE
• CAS NO: 205526-22-3
• Molecular Formula: C₂₄H₂₀ClNO₄
• Molecular Weight: 421.87
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids;Peptide;a-amino;unnatural amino acids
• Mol File: 205526-22-3.mol

Chemical Properties

• Melting Point: 154°C
• Boiling Point: 640.9 °C at 760 mmHg
• Flash Point: 341.4 °C
• Appearance: /
• Density: 1.337 g/cm³
• Storage Temp.: 2-8°C
• PKA: 3.72±0.11(Predicted)
• CAS DataBase Reference: FMOC-D-2-Chlorophe(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-D-2-Chlorophe(205526-22-3)
• EPA Substance Registry System: FMOC-D-2-Chlorophe(205526-22-3)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 205526-22-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
FMOC-D-2-Chlorophe is used as a protective agent for amino acids during the synthesis of peptides. It shields the amino group, enabling selective deprotection and subsequent modifications, which is crucial for the precise construction of peptide sequences.
Used in Chemical Research:
In the realm of chemical research, FMOC-D-2-Chlorophe is utilized as a reagent to facilitate the synthesis of complex organic molecules. Its compatibility with a range of chemical reactions makes it a valuable asset in the development of new compounds and materials.
Used in Solid-Phase Peptide Synthesis:
FMOC-D-2-Chlorophe is employed as a key component in solid-phase peptide synthesis techniques. It allows for the stepwise addition of amino acids to a growing peptide chain, with the protective group ensuring that only the desired amino group is deprotected and reacted at each stage of the synthesis process. This selective protection is vital for the successful synthesis of large and complex peptides.