207115-22-8

Basic information

• Product Name: 4-BROMO-2-IODOPHENOL
• Synonyms: 4-BROMO-2-IODOPHENOL;2-Iodo-4-bromophenol;4-Bromo-2-iodophenol 98%;4-Bromo-2-iodophenol98%
• CAS NO: 207115-22-8
• Molecular Formula: C₆H₄BrIO
• Molecular Weight: 298.90383
• Mol File: 207115-22-8.mol
• Article Data: 11

Chemical Properties

• Melting Point: 90℃ (ethanol )
• Boiling Point: 243.0±25.0℃ (760 Torr)
• Flash Point: 100.8±23.2℃
• Appearance: /
• Density: 2.369±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 7.94±0.18(Predicted)
• CAS DataBase Reference: 4-BROMO-2-IODOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-IODOPHENOL(207115-22-8)
• EPA Substance Registry System: 4-BROMO-2-IODOPHENOL(207115-22-8)

Safety Data

• Hazardous Substances Data: 207115-22-8(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-iodophenol is a chemical compound with the molecular formula C6H4BrIO. It is a derivative of phenol and is used in various organic synthesis processes, particularly in pharmaceutical and agrochemical production. 4-BROMO-2-IODOPHENOL is known for its high reactivity and is frequently used as a building block in the construction of more complex molecules. Its unique structure and properties make it a valuable component in the development of new materials and compounds for a wide range of industrial applications. Additionally, 4-Bromo-2-iodophenol is also used as a reagent in research laboratories for various chemical and biological experiments.

InChI:InChI=1S/C6H4BrIO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H

Upstream product

• 533-58-4 2-Iodophenol 
• 40925-68-6 2-amino-4-bromo-phenol 
• 108-95-2 phenol 
• 106-41-2 4-bromo-phenol 
• 15459-51-5 2,6-di-iodo-4-bromophenol 

Downstream Products

• 15459-51-5 2,6-di-iodo-4-bromophenol 
• 612833-66-6 1-(benzyloxy)-4-bromo-2-iodobenzene 
• 1354655-81-4 C₁₂H₈Br₂INO 
• 1354655-80-3 C₁₂H₆Br₂INO₃ 
• 1400276-50-7 C₁₂H₅Br₂FINO₃ 
• 1431639-03-0 C₁₇H₂₇BrOSi₂ 
• 1318697-61-8 C₁₂H₁₈BrIOSi 
• 1443156-04-4 4-(5-bromo-2-hydroxy-phenylethynyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1443156-06-6 4-[5-(4-methanesulfonyl-phenyl)-benzofuran-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1443156-07-7 4-[5-(4-methanesulfonyl-phenyl)-2,3-dihydro-benzofuran-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 1382136-41-5 4-[5-(4-methanesulfonyl-phenyl)-2,3-dihydro-benzofuran-2-yl]-piperidine 
• 1581276-06-3 4-bromo-2-(hex-1-yn-1-yl)phenyl acetate 
• 1581276-40-5 C₁₈H₁₆BBrO₃ 
• 1581276-07-4 4-bromo-2-(hex-1-yn-1-yl)phenol 

Relevant articles and documents

One-Pot Benzo[b]phosphole Synthesis through Sequential Alkyne Arylmagnesiation, Electrophilic Trapping, and Intramolecular Phospha-Friedel-Crafts Cyclization

A one-pot multicomponent synthesis of a benzo[b]phosphole derivative has been achieved by a sequence of transition-metal-catalyzed arylmagnesiation of an internal alkyne, electrophilic trapping of the resulting alkenylmagnesium species with a dichloroorganophosphine, and an intramolecular phospha-Friedel-Crafts reaction. With appropriate arylmagnesiation and P-C bond formation conditions, the present method allows for the modular and expedient preparation of benzophospholes bearing a variety of substituents on the phosphorus atom, the C2 and C3 atoms, and the benzo moiety.

A convenient and efficient H2SO4-promoted regioselective monobromination of phenol derivatives using N-bromosuccinimide

A convenient, rapid H2SO4-promoted regioselective monobromination reaction with N-bromosuccinimide was developed. The desired para-monobrominated or ortho-monobrominated products of phenol derivatives were obtained in good to excellent yields with high selectivity. Regioselective chlorination and iodination were also achieved in the presence of H2SO4 using N-chlorosuccinimide and N-iodosuccinimide, respectively.

Isoquinolinium Dichromate and Chlorochromate as Efficient Catalysts for Oxidative Halogenation of Aromatic Compounds under Acid-Free Conditions

Isoquinolinium dichromate and isoquinolinium chlorochromate were found as efficient catalysts to trigger oxidative bromination and iodination of aromatic hydrocarbons with KBr/KI and KHSO4 under acid-free conditions. Reaction times reduced highly significantly under sonication, followed by corresponding mono bromo derivatives in very good yield with high regioselectivity.