Welcome to LookChem.com Sign In|Join Free

Cas Database

20780-53-4

20780-53-4

Identification

  • Product Name:Oxirane, 2-phenyl-,(2R)-

  • CAS Number: 20780-53-4

  • EINECS:202-476-7

  • Molecular Weight:120.151

  • Molecular Formula: C8H8O

  • HS Code:29109000

  • Mol File:20780-53-4.mol

Synonyms:Benzene,(epoxyethyl)-, (R)-(+)- (8CI);Oxirane, phenyl-, (2R)- (9CI);Oxirane, phenyl-,(R)-;(+)-(R)-Styrene oxide;(+)-Phenyloxirane;(+)-Styrene oxide;(2R)-2-Phenyloxirane;(2R)-Phenyloxirane;(R)-(+)-Phenyloxirane;(R)-(+)-Styrene epoxide;(R)-2-Phenyloxirane;(R)-Epoxystyrene;(R)-Phenylethylene oxide;(R)-Phenyloxirane;(R)-Styrene 7,8-oxide;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Pictogram(s):ToxicT

  • Hazard Codes:T

  • Signal Word:Danger

  • Hazard Statement:H312 Harmful in contact with skinH319 Causes serious eye irritation H350 May cause cancer

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:Usbiological
  • Product Description:R-Styrene oxide
  • Packaging:1g
  • Price:$ 380
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:(R)-Styrene Oxide
  • Packaging:10g
  • Price:$ 225
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:(R)-Styrene Oxide >96.0%(GC)
  • Packaging:25g
  • Price:$ 142
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:(R)-Styrene Oxide >96.0%(GC)
  • Packaging:5g
  • Price:$ 48
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:(R)-(+)-Styrene oxide 97%, optical purity ee: 97% (GLC)
  • Packaging:25g
  • Price:$ 401
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:(R)-(+)-Styrene oxide ChiPros
  • Packaging:100g
  • Price:$ 1070
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:(R)-(+)-Styrene oxide ChiPros
  • Packaging:25g
  • Price:$ 281
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:(R)-(+)-Styrene oxide 97%, optical purity ee: 97% (GLC)
  • Packaging:5g
  • Price:$ 150
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Oakwood
  • Product Description:(R)-2-Phenyloxirane
  • Packaging:25g
  • Price:$ 208
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Oakwood
  • Product Description:(R)-2-Phenyloxirane
  • Packaging:100g
  • Price:$ 678
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 250 Articles be found

Unusual solvent-effect in stereochemistry of asymmetric epoxidation using a (salen)chromium(III) complex as a catalyst

Imanishi, Hirotoshi,Katsuki, Tsutomu

, p. 251 - 254 (1997)

Epoxidation of conjugated olefins has been examined with (salen)chromium(III) complexes as catalysts. Although (salen)chromium(III) complexes were catalytically less active than the corresponding (salen)manganese(III) complexes, the reactions with the chromium complexes were found to exhibit interesting solvent-dependent stereochemistry.

Catalytic asymmetric epoxidation with a chiral ruthenium porphyrin and N-oxides

Berkessel, Albrecht,Frauenkron, Matthias

, p. 2265 - 2266 (1997)

The enantiomerically pure ruthenium porphyrin 3 was synthesized in very high yield by refluxing the porphyrin 2 with Ru3(CO)12 in phenol; its subsequent use in the catalytic asymmetric epoxidation of olefins with 2,6-dichloropyridine

Asymmetric epoxidation of styrene by novel chiral ruthenium(II) Schiff base complexes, synthesis and characterization

Kureshy,Khan,Abdi,Bhatt

, p. 1693 - 1701 (1993)

Synthesis of some novel Chiral Ru(II) Schiff base complexes of the type [Rul(PPh3)(H2O)2] 1-6 where L = Chiral Schiff bases derived from salicylaldehyde and L-amino acids namely, L-alanine, L-valine, L-Serine, L-Arginine,

A novel enantiopure proline-derived triazacyclononane: Synthesis, structure and application of its manganese complex

Bolm,Meyer,Raabe,Weyhermuller,Bothe

, p. 2435 - 2436 (2000)

The X-ray crystal structure and electrochemical data of a manganese complex [L2Mn2(III)(μ-O)(μ-AcO)2][PF6]2 with L being an enantiopure C3-symmetric 1,4,7-triazacyclononane derived from L-p

Confinement of CuII-phthalocyanine in a bioinspired hybrid nanoparticle-assembled structure yields selective and stable epoxidation catalysts

Manna, Joydeb,Amali, Arlin Jose,Rana, Rohit Kumar

, p. 8453 - 8457 (2014)

Herein, we demonstrate that a bioinspired assembly of silica nanoparticles with polyamines as structure-directing agents similar to that known for the biosilicification of diatoms can pave the way for the efficient encapsulation of sulfonated copper-phthalocyanine in a hybrid microcapsule structure, in which the organic component provides a capable environment for its catalytic activity in epoxidation reactions and the nanoassembled structure imparts stability.

Bis-Faced Aminoporphyrin Templates for the Synthesis of Chiral Catalysts and Hemeprotein Analogues

Rose, Eric,Soleilhavoup, Michele,Christ-Tommasino, Lorraine,Moreau, Gilles,Collman, James P.,et al.

, p. 2042 - 2044 (1998)

-

Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins

Escot, Lorena,González-Granda, Sergio,Gotor-Fernández, Vicente,Lavandera, Iván

, p. 2552 - 2560 (2022/02/16)

A concurrent cascade combining the use of a gold(I) N-heterocyclic carbene (NHC) and an alcohol dehydrogenase (ADH) is disclosed for the synthesis of highly valuable enantiopure halohydrins in an aqueous medium and under mild reaction conditions. The meth

Enantiomer Separation of Nitriles and Epoxides by Crystallization with Chiral Organic Salts: Chirality Switching Modulated by Achiral Acids

Hirose, Takuji,Kodama, Koichi,Shimomura, Yuki

, p. 6552 - 6557 (2021/11/16)

Enantiomer separation of nitriles and epoxides by inclusion crystal formation with organic-salt type chiral hosts was achieved. The stereochemistry of the preferentially included nitrile could be switched only by changing the achiral carboxylic acid component. Crystallographic analysis of the inclusion crystals reveals that the hydrogen-bonding networks are controlled by the acidity of the phenol group of the acids, which results in chirality switching.

A new clade of styrene monooxygenases for (R)-selective epoxidation

Xiao, Hu,Dong, Shuang,Liu, Yan,Pei, Xiao-Qiong,Lin, Hui,Wu, Zhong-Liu

, p. 2195 - 2201 (2021/04/12)

Styrene monooxygenases (SMOs) are excellent enzymes for the production of (S)-enantiopure epoxides, but so far, only one (R)-selective SMO has been identified with a narrow substrate spectrum. Mining the NCBI non-redundant protein sequences returned a new distinct clade of (R)-selective SMOs. Among them,SeStyA fromStreptomyces exfoliatus,AaStyA fromAmycolatopsis albispora, andPbStyA fromPseudonocardiaceaewere carefully characterized and found to convert a spectrum of styrene analogues into the corresponding (R)-epoxides with up to >99% ee. Moreover, site 46 (AaStyA numbering) was identified as a critical residue that affects the enantioselectivity of SMOs. Phenylalanine at site 46 was required for the (R)-selective SMO to endow excellent enantioselectivity. The identification of new (R)-selective SMOs would add a valuable green alternative to the synthetic tool box for the synthesis of enantiopure (R)-epoxides.

An Amphiphilic (salen)Co Complex – Utilizing Hydrophobic Interactions to Enhance the Efficiency of a Cooperative Catalyst

Solís-Mu?ana, Pablo,Salam, Joanne,Ren, Chloe Z.-J.,Carr, Bronte,Whitten, Andrew E.,Warr, Gregory G.,Chen, Jack L.-Y.

supporting information, p. 3207 - 3213 (2021/06/01)

An amphiphilic (salen)Co(III) complex is presented that accelerates the hydrolytic kinetic resolution (HKR) of epoxides almost 10 times faster than catalysts from commercially available sources. This was achieved by introducing hydrophobic chains that increase the rate of reaction in one of two ways – by enhancing cooperativity under homogeneous conditions, and increasing the interfacial area under biphasic reaction conditions. While numerous strategies have been employed to increase the efficiency of cooperative catalysts, the utilization of hydrophobic interactions is scarce. With the recent upsurge in green chemistry methods that conduct reactions ‘on water’ and at the oil-water interface, the introduction of hydrophobic interactions has potential to become a general strategy for enhancing the catalytic efficiency of cooperative catalytic systems. (Figure presented.).

Structural and Biochemical Studies Enlighten the Unspecific Peroxygenase from Hypoxylon sp. EC38 as an Efficient Oxidative Biocatalyst

Ebner, Katharina,Glieder, Anton,Kroutil, Wolfgang,Mattevi, Andrea,Rinnofner, Claudia,Rotilio, Laura,Swoboda, Alexander

, p. 11511 - 11525 (2021/09/22)

Unspecific peroxygenases (UPOs) are glycosylated fungal enzymes that can selectively oxidize C-H bonds. UPOs employ hydrogen peroxide as the oxygen donor and reductant. With such an easy-to-handle cosubstrate and without the need for a reducing agent, UPOs are emerging as convenient oxidative biocatalysts. Here, an unspecific peroxygenase from Hypoxylon sp. EC38 (HspUPO) was identified in an activity-based screen of six putative peroxygenase enzymes that were heterologously expressed in Pichia pastoris. The enzyme was found to tolerate selected organic solvents such as acetonitrile and acetone. HspUPO is a versatile catalyst performing various reactions, such as the oxidation of prim- and sec-alcohols, epoxidations, and hydroxylations. Semipreparative biotransformations were demonstrated for the nonenantioselective oxidation of racemic 1-phenylethanol rac-1b (TON = 13 000), giving the product with 88% isolated yield, and the oxidation of indole 6a to give indigo 6b (TON = 2800) with 98% isolated yield. HspUPO features a compact and rigid three-dimensional conformation that wraps around the heme and defines a funnel-shaped tunnel that leads to the heme iron from the protein surface. The tunnel extends along a distance of about 12 ? with a fairly constant diameter in its innermost segment. Its surface comprises both hydrophobic and hydrophilic groups for dealing with substrates of variable polarities. The structural investigation of several protein-ligand complexes revealed that the active site of HspUPO is accessible to molecules of varying bulkiness with minimal or no conformational changes, explaining the relatively broad substrate scope of the enzyme. With its convenient expression system, robust operational properties, relatively small size, well-defined structural features, and diverse reaction scope, HspUPO is an exploitable candidate for peroxygenase-based biocatalysis.

Process route upstream and downstream products

Process route

Conditions
Conditions Yield
With oxygen; isobutyraldehyde; In acetonitrile; at 45 ℃; for 8h; enantioselective reaction;
85%
10%
5%
With iodosylbenzene; Na4-(R)-HPBA-DMP)>*H2O (3); In acetonitrile; at -2 - 0 ℃; for 24h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With iodosylbenzene; square planar cobalt(II) complexes; In acetonitrile; at -2 - 0 ℃; for 24h; Product distribution; other styrenes, different complexes;
With tert.-butylhydroperoxide; oxygen; at 80 ℃; for 4h; optical yield given as %ee; enantioselective reaction; Neat (no solvent);
With C32H31MnN2O7*H2O; dihydrogen peroxide; In acetonitrile; at -20 ℃; for 36h; Solvent; Temperature; enantioselective reaction;
26 % ee
With dihydrogen peroxide; In acetonitrile; at 0 ℃; for 27h; Reagent/catalyst; Temperature; Solvent; enantioselective reaction;
71 % ee
With oxygen; isobutyraldehyde; In acetonitrile; at 25 ℃; for 4h; enantioselective reaction; Catalytic behavior; Green chemistry;
41 %Chromat.
13 %Chromat.
47 %Chromat.
With oxygen; isobutyraldehyde; In acetonitrile; at 40 ℃; for 2h; under 750.075 Torr; Reagent/catalyst; Solvent; Temperature; enantioselective reaction; Catalytic behavior;
65 %Chromat.
13 %Chromat.
22 %Chromat.
With oxygen; isobutyraldehyde; In acetonitrile; at 45 ℃; for 4h; under 760.051 Torr; Reagent/catalyst; Solvent; Temperature; enantioselective reaction; Catalytic behavior;
81 % ee
With oxygen; isobutyraldehyde; In acetonitrile; at 60 ℃; for 2h; under 760.051 Torr; Solvent; Temperature; Reagent/catalyst; enantioselective reaction;
12 %Chromat.
77 %Chromat.
11 %Chromat.
With tert.-butylhydroperoxide; oxygen; In neat (no solvent); at 80 ℃; for 4h; under 760.051 Torr; Reagent/catalyst; Time; Catalytic behavior;
14 % ee
With phenylacetic acid; dihydrogen peroxide; In ethanol; at 25 ℃; pH=7; Time; Reagent/catalyst; stereoselective reaction; Enzymatic reaction;
39 % ee
With dihydrogen peroxide; (R)-ibuprofene; In ethanol; at 25 ℃; pH=7; Reagent/catalyst; Time; stereoselective reaction; Enzymatic reaction;
88 % ee
With tert.-butylhydroperoxide; oxygen; at 80 ℃; for 12h; under 760.051 Torr; Temperature; Time; Reagent/catalyst; enantioselective reaction; Catalytic behavior; Green chemistry;
16 % ee
(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

(S)-styrene oxide
20780-54-5

(S)-styrene oxide

phenylacetaldehyde
122-78-1

phenylacetaldehyde

benzaldehyde
100-52-7

benzaldehyde

Conditions
Conditions Yield
With NH-pyrazole; D2-symmetric chiral dioxoruthenium(VI) porphyrin; In benzene; for 12h; Yield given; Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
27%
12%
With NH-pyrazole; D2-symmetric chiral dioxoruthenium(VI) porphyrin; In benzene; Yields of byproduct given; Ambient temperature;
12%
27%
With NH-pyrazole; D2-symmetric chiral dioxoruthenium(VI) porphyrin; In benzene; for 12h; Product distribution; Ambient temperature; further solvents; also without pyrazole; further chiral reagents;
27%
12%
With NH-pyrazole; oxygen; trans-dioxo(D4-porphyrinato)ruthenium(VI); In dichloromethane; for 24h; under 6080 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
With dihydrogen peroxide; F43Y mutant of human myoglobin; at 0 ℃; for 0.0833333h; Product distribution; Mechanism; var. conc., catalyst, addition of mannitol or diethylenetriaminepentaacetic acid;
29 % Chromat.
7 % Chromat.
With (ClO4)2; In acetonitrile; at 25 ℃; for 12h; Product distribution; other reagents, asymmetric epoxidation;
11 % Chromat.
4 % Chromat.
With hydrogen (18)O-peroxide; H64D myoglobin; In phosphate buffer; at 20 ℃; pH=7.0; Further Variations:; Catalysts; Enzyme kinetics; Enzymatic reaction;
With tert.-butylhydroperoxide; In acetonitrile; at 70 ℃; Reagent/catalyst; Optical yield = 62 %ee; enantioselective reaction; Inert atmosphere;
Conditions
Conditions Yield
With sodium hypochlorite; 7.6SBA-PrSO3Mn(salen); for 24h; Further Variations:; Reagents; reaction times; Product distribution;
styrene oxide
96-09-3

styrene oxide

phenylethane 1,2-diol
93-56-1

phenylethane 1,2-diol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

(S)-styrene oxide
20780-54-5

(S)-styrene oxide

Conditions
Conditions Yield
With water; dimeric chiral (salen)Co complex linked with Al; at 20 ℃; for 12h; Further Variations:; Catalysts; Product distribution;
28%
In ethanol; at 27 ℃; for 7h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Aspergillus niger, pH 7;
With Bacillus megaterium ECU1001 cell-free extract; In potassium phosphate buffer; dimethyl sulfoxide; at 30 ℃; for 0.5h; pH=7; optical yield given as %ee; enantioselective reaction; Resolution of racemate; Enzymatic reaction;
With (R,R)-Salen-Co-OTs; water; In neat (no solvent); at 20 ℃; for 3h; enantioselective reaction; Resolution of racemate; Inert atmosphere; Schlenk technique;
73 % ee
styrene oxide
96-09-3

styrene oxide

phenylethane 1,2-diol
93-56-1

phenylethane 1,2-diol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

Conditions
Conditions Yield
With water; C71H111CoN2O9S; In neat (no solvent); at 20 ℃; for 3h; enantioselective reaction; Resolution of racemate; Inert atmosphere; Schlenk technique;
> 99 % ee
1-chloroacetophenone
532-27-4,108321-66-0,164322-25-2

1-chloroacetophenone

phenylethane 1,2-diol
93-56-1

phenylethane 1,2-diol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

2-chloro-1-phenylethanol
56751-12-3

2-chloro-1-phenylethanol

Conditions
Conditions Yield
1-chloroacetophenone; With isopropyl alcohol; at 30 ℃; for 4h; aq. buffer; Enzymatic reaction;
With Agrobacterium radiobacter AD1 halohydrin dehalogenase HheC; at 30 ℃; for 20h; stereoselective reaction; aq. buffer; Enzymatic reaction;
72 %Chromat.
10 %Chromat.
3 %Chromat.
2-Bromo-1-phenylethanol
2425-28-7

2-Bromo-1-phenylethanol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

(S)-styrene oxide
20780-54-5

(S)-styrene oxide

(S)-2-bromo-1-phenylethanol
2425-28-7,73908-23-3,74497-33-9,76155-80-1

(S)-2-bromo-1-phenylethanol

Conditions
Conditions Yield
With recombinant alphaproteobacterium halohydrin dehalogenase; In ethanol; at 30 ℃; for 0.333333h; pH=8.0; enantioselective reaction; Enzymatic reaction;
> 99 % ee
52.8 % ee
Conditions
Conditions Yield
With sodium hypochlorite; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; In water; at 0 ℃; for 2h; optical yield given as %ee; enantioselective reaction;
87%
With iodosylbenzene; chiral Mn-binaphthyl Schiff base; In benzene; at 25 ℃; for 1h; Product distribution; other solvent; other temp.; other reaction time;
82%
With dihydrogen peroxide; C120H92N4O6Ti2; In water; ethyl acetate; at 25 ℃; for 24h; Product distribution / selectivity;
73%
at -10 ℃;
64%
With dihydrogen peroxide; C64H64N4O6Ti2; In dichloromethane; water; at 25 ℃; for 24h; Product distribution / selectivity;
47%
styrene; With AD-mix-β; In water; tert-butyl alcohol; at 0 ℃; for 18h;
With pyridine; p-toluenesulfonyl chloride; at 0 ℃; for 13h;
With sodium hydroxide; In diethyl ether; water; at 20 ℃; for 3h;
With iodosylbenzene; C28H34ClMnN2O8S2(2-)*56H2O*40Zn(2+)*64HO(1-)*14NO3(1-); ammonium acetate; In dichloromethane; at 0 ℃; for 6h; Reagent/catalyst; Catalytic behavior;
99 % ee
With tert.-butylhydroperoxide; C15H15I2MoN2O3; In decane; dichloromethane; at 54.84 ℃; Reagent/catalyst; enantioselective reaction;
With sodium hypochlorite; disodium hydrogenphosphate; 4-Phenylpyridine 1-oxide; 25,27-bis-{2,2'-[(1R,2R)-(1,2-diphenyl)-1,2-ethanediyl-bis-[nitrilomethyl-(2-hydroxy-3,1-phenylene)-oxy]]-ethoxy-N,N',O,O'}-26,28-bis-propyloxy-calix[4]arene-1,3-alternated manganese(III); In dichloromethane; water; at 25 ℃; for 24h; pH=11.2; Reagent/catalyst; Inert atmosphere;
85 %Chromat.
With tert.-butylhydroperoxide; sodium carbonate; In chloroform; water; at 70 ℃; for 24h; Autoclave;
With cytochrome P450BM3 peroxygenase F87A-T268V mutant; dihydrogen peroxide; In methanol; aq. phosphate buffer; at 25 ℃; for 0.5h; enantioselective reaction; Catalytic behavior;
91 % ee
With ruthenium trichloride; Trimethylacetic acid; In dichloromethane; at 0 ℃; for 24h; pH=7; Reagent/catalyst; Solvent; Temperature; enantioselective reaction; Enzymatic reaction;
99 % ee
With P450 monoxygenase L75V-V78F-F87V-L181F-L262V-A328F-L437V-T438F mutant; ammonium formate; NADPH; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; pH=8; Reagent/catalyst; enantioselective reaction; Sealed tube; Enzymatic reaction;
96 % ee
With oxygen; isobutyraldehyde; In acetonitrile; at 52 ℃; for 6h; enantioselective reaction;
99 % ee
With E. coli cells containing FAD-dependent styrene monooxygenase from Streptomyces exfoliatus and NADH-dependent flavin oxidoreductase from Pseudomonas sp. LQ26; In aq. phosphate buffer; isopropyl alcohol; at 30 ℃; for 2h; pH=7; Reagent/catalyst; enantioselective reaction; Kinetics; Catalytic behavior; Enzymatic reaction;
95 % ee
(1R)-2-O-methanesulfonyl-1-phenyl-1,2-ethanediol
343239-88-3

(1R)-2-O-methanesulfonyl-1-phenyl-1,2-ethanediol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

Conditions
Conditions Yield
With sodium methylate; In methanol; at 20 ℃; for 1h;
90%
(R)-2-bromo-1-phenylethanol
73908-23-3

(R)-2-bromo-1-phenylethanol

(R)-Styrene oxide
20780-53-4

(R)-Styrene oxide

Conditions
Conditions Yield
With potassium hydroxide; In chloroform; water; optical yield given as %ee;
100%
With potassium hydroxide; In chloroform; at 40 ℃; for 3h;
78%
With sodium hydroxide; In diethyl ether; pentane; Yield given;
With sodium hydroxide; In diethyl ether; pentane; for 0.25h;
0.595 g
With sodium hydroxide; In methanol; at 0 ℃; for 1h;

Global suppliers and manufacturers

Global( 120) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Simagchem Corporation
  • Business Type:Manufacturers
  • Contact Tel:+86-592-2680277
  • Emails:sale@simagchem.com
  • Main Products:110
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Trading Company
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
  • Chemwill Asia Co., Ltd.
  • Business Type:Manufacturers
  • Contact Tel:021-51086038
  • Emails:sales@chemwill.com
  • Main Products:30
  • Country:China (Mainland)
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
  • Shaanxi BLOOM TECH Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-29-86470566
  • Emails:sales@bloomtechz.com
  • Main Products:80
  • Country:China (Mainland)
  • Shanghai Upbio Tech Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-21-52196435
  • Emails:upbiocn@hotmail.com
  • Main Products:88
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 20780-53-4
Post Buying Request Now
close
Remarks: The blank with*must be completed