209459-11-0

Basic information

• Product Name: 7-Benzothiazolecarboxylicacid,2-amino-,methylester
• Synonyms: 7-Benzothiazolecarboxylicacid,2-amino-,methylester;7-Benzothiazolecarboxylicacid,2-amino-,methylester(9CI);Methyl 2-aMinobenzo[d]thiazole-7-carboxylate;Methyl 2-aMino-1,3-benzothiazole-7-carboxylate;2-AMino-benzothiazole-7-carboxylic acid Methyl ester;2-amino-7-Benzothiazolecarboxylic acid methyl ester
• CAS NO: 209459-11-0
• Molecular Formula: C₉H₈N₂O₂S
• Molecular Weight: 208.23702
• Product Categories: AMINOACID;BENZOTHIAZOLE
• Mol File: 209459-11-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 378.379°C at 760 mmHg
• Flash Point: 182.638°C
• Appearance: /
• Density: 1.422g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.7
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.26±0.30(Predicted)
• CAS DataBase Reference: 7-Benzothiazolecarboxylicacid,2-amino-,methylester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Benzothiazolecarboxylicacid,2-amino-,methylester(209459-11-0)
• EPA Substance Registry System: 7-Benzothiazolecarboxylicacid,2-amino-,methylester(209459-11-0)

Safety Data

• Hazardous Substances Data: 209459-11-0(Hazardous Substances Data)

Usage

Uses

Methyl 2-aminobenzo[d]thiazole-7-carboxylate was used a a reactant in the creation of spirocyclic hydantoin antagonists of LFA-1.

InChI:InChI=1/C9H8N2O2S/c1-13-8(12)5-3-2-4-6-7(5)14-9(10)11-6/h2-4H,1H3,(H2,10,11)

Upstream product

• 1038509-28-2 methyl benzo[d]thiazole-7-carboxylate 
• 3425-46-5 potassium selenocyanate 
• 4518-10-9 Methyl 3-aminobenzoate 
• 192948-00-8 methyl 3-thioureidobenzoate 

Downstream Products

• 1038509-28-2 methyl benzo[d]thiazole-7-carboxylate 
• 677304-83-5 benzo[d]thiazole-7-carboxylic acid 
• 124371-49-9 benzothiadiazole-7-carboxylic acid chloride 
• 35272-27-6 benzo[d][1,2,3]thiadiazole-7-carboxylic acid 
• 123158-77-0 2-amino-5-methyl-3-nitrophenyliodide 

Relevant articles and documents

Iodine-catalyzed amination of benzothiazoles with KSeCN in water to access primary 2-aminobenzothiazoles

A facile and sustainable approach for the amination of benzothiazoles with KSeCN using iodine as the catalyst in water has been disclosed under transition-metal free conditions. The reaction proceeded smoothly to afford various primary 2-amino benzothiazoles in up to 96% yield. A series of control experiments were performed, suggesting a ring-opening mechanism was involved via a radical process. This protocol provides efficient synthesis of primary 2-aminobenzothiazoles

TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES

The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R1 are as described in the description, and to the use of such compounds, or of pharmaceutically acceptable salts of such compounds, as medicaments, especially as orexin receptor antagonists.