21149-26-8Relevant articles and documents
Reaction of purines with hydroxyl radical generated by photolysis of mercaptopyridine-N-oxides
Vieira,Telo,Dias
, p. 318 - 325 (2007/10/03)
The UV-photolysis of 4-mercaptopyridine-N-oxyde in aqueous solution is shown to be an efficient method of generating HO. radicals, as an alternative to the radiolysis of water. The reaction of adenine with HO. produced by the photolytic method resulted in the formation of 8-hydroxyadenine and 4,6-diamino-5-formamidopyrimidine in conditions and yields similar to those observed when HO. is produced by water radiolysis. ESR studies of the transients formed upon reaction of HO. with xanthine showed the formation of a radical anion in neutral conditions and a radical dianion at high pH values, due to the oxidation of the substrate by the conjugate base of HO., the O.- radical.
Pattern of OH radical reaction with adenine and its nucleosides and nucleotides. Characterization of two types of isomeric OH adduct and their unimolecular transformation reactions
Vieira,Steenken
, p. 6986 - 6994 (2007/10/02)
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