2124-31-4

Basic information

• Product Name: 4'-DIMETHYLAMINOACETOPHENONE
• Synonyms: 4'-DIMETHYLAMINOACETOPHENONE;4'-(N,N-DIMETHYLAMINO)ACETOPHENONE;4-(N,N-DIMETHYLAMINO)ACETOPHENONE;TIMTEC-BB SBB007875;P-(DIMETHYLAMINO)ACETOPHENONE;1-(4-Dimethylamino-phenyl)-ethanone;1-[4-(dimethylamino)phenyl]-ethanon;1-[4-(Dimethylamino)phenyl]ethanone
• CAS NO: 2124-31-4
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Product Categories: Amines;blocks;Aromatic Acetophenones & Derivatives (substituted);Benzene series
• Mol File: 2124-31-4.mol
• Article Data: 67

Chemical Properties

• Melting Point: 105°C
• Boiling Point: 282.9 °C at 760 mmHg
• Flash Point: 107 °C
• Appearance: /
• Density: 1.026 g/cm³
• Vapor Pressure: 0.00327mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.16±0.12(Predicted)
• CAS DataBase Reference: 4'-DIMETHYLAMINOACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-DIMETHYLAMINOACETOPHENONE(2124-31-4)
• EPA Substance Registry System: 4'-DIMETHYLAMINOACETOPHENONE(2124-31-4)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 2124-31-4(Hazardous Substances Data)

Usage

Chemical Properties

off-white crystalline powder

Uses

4''-Dimethylaminoacetophenone

InChI:InChI=1/C10H13NO/c1-8(12)9-4-6-10(7-5-9)11(2)3/h4-7H,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 99-92-3 p-aminobenzophenone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 99-91-2 para-chloroacetophenone 
• 124-40-3 dimethyl amine 
• 114890-27-6 2,3-bis-(4-dimethylamino-phenyl)-butane-2,3-diol 
• 320349-36-8 C₁₀H₁₄NO 
• 108-24-7 acetic anhydride 
• 121-69-7 N,N-dimethyl-aniline 
• 38447-66-4 acetyl phenyl selenide 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 68-12-2 N,N-dimethyl-formamide 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 

Downstream Products

• 121167-59-7 1-(4-dimethylamino-phenyl)-ethanone-phenylhydrazone 
• 317333-82-7 1-(3-benzylphenyl)-3-(5-dimethylaminopyridin-2-yl)-propane-1,3-dione 
• 20449-17-6 1-(4-N,N-dimethylaminophenyl)-1,3-butadione 
• 210832-81-8 2,2-dibromo-1-(4-(dimethylamino)phenyl)ethan-1-one 
• 37904-72-6 2-bromo-1-(4-(dimethylamino)phenyl)ethanone 
• 858598-10-4 ethyl 5-(4-dimethylaminophenyl)-1-(6-methoxy-3-pyridyl)-1H-pyrazole-3-carboxylate 
• 127034-22-4 (E)-1-(2,5-dimethoxyphenyl)-3-(4-N,N-dimethylaminophenyl)prop-2-en-1-one 
• 187672-34-0 4-dimethylaminoacetophenone oxime 
• 117994-77-1 1-(4-Dimethylamino-phenyl)-4,4,4-trifluoro-butane-1,3-dione 

Relevant articles and documents

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Cooperative electron transfer fragmentation reactions. Amplification of a photoreaction through a tandem chain fragmentation of acceptor and donor pinacols

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Reductive Arylation of Amides via a Nickel-Catalyzed Suzuki–Miyaura-Coupling and Transfer-Hydrogenation Cascade

We report a means to achieve the addition of two disparate nucleophiles to the amide carbonyl carbon in a single operational step. Our method takes advantage of non-precious-metal catalysis and allows for the facile conversion of amides to chiral alcohols via a one-pot Suzuki–Miyaura cross-coupling/transfer-hydrogenation process. This study is anticipated to promote the development of new transformations that allow for the conversion of carboxylic acid derivatives to functional groups bearing stereogenic centers via cascade processes.

Ruthenium-Catalyzed Dehydrogenation of Alcohols with Carbodiimide via a Hydrogen Transfer Mechanism

Ruthenium-catalyzed oxidative dehydrogenation of alcohols using carbodiimide as an efficient hydrogen acceptor has been developed. The protocol exhibits wide substrate scope with good to excellent yields. The results of the kinetic analysis indicated that the reaction mechanism includes the hydrogen transfer process and that the addition of carbodiimide is essential for the reaction system, and the resulting amidine also could react as a hydrogen acceptor.