21366-63-2

Basic information

• Product Name: cannabicyclol
• Synonyms: cannabicyclol;(1aR)-1a,2,3,3a,8bβ,8cβ-Hexahydro-1,1,3aβ-trimethyl-6-pentyl-1H-4-oxa-benzo[f]cyclobut[cd]inden-8-ol;Cannabipinol
• CAS NO: 21366-63-2
• Molecular Formula: C₂₁H₃₀O₂
• Molecular Weight: 314.466
• Mol File: 21366-63-2.mol

Chemical Properties

• Melting Point: 145-146 °C
• Boiling Point: 382.1°Cat760mmHg
• Flash Point: 145.6°C
• Appearance: /
• Density: 1.068g/cm³
• Vapor Pressure: 2.2E-06mmHg at 25°C
• Refractive Index: 1.55
• PKA: 9.94±0.60(Predicted)
• CAS DataBase Reference: cannabicyclol(CAS DataBase Reference)
• NIST Chemistry Reference: cannabicyclol(21366-63-2)
• EPA Substance Registry System: cannabicyclol(21366-63-2)

Safety Data

• Hazardous Substances Data: 21366-63-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C21H30O2/c1-5-6-7-8-13-11-15(22)17-16(12-13)23-21(4)10-9-14-18(21)19(17)20(14,2)3/h11-12,14,18-19,22H,5-10H2,1-4H3

Upstream product

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Relevant articles and documents

Photochemistry of Cannabidiol (CBD) Revised. A Combined Preparative and Spectrometric Investigation

Cannabis is a plant with an astonishing ability to biosynthesize cannabinoids, and more than 100 molecules belonging to this class have been isolated. Among them in recent years cannabidiol (CBD) has received the interest of pharmacology as the major nonpsychotropic cannabinoid with many potential clinical applications. Although the reactivity of CBD has been widely investigated, only little attention has been given to the possible photodegradation of this cannabinoid, and the data available in the literature are outdated and, in some cases, conflicting. The aim of the present work is providing a characterization of the photochemical behavior of CBD in organic solvents, through a detailed GC-MS analyses, isolation, and NMR characterization of the photoproducts obtained.

METHODS OF SYNTHESIZING HIGH-PURITY CANNABICYCLOL AND ARTIFICIAL RESINS COMPRISING CANNABICYCLOL

Compositions having enhanced cannabicyclol (CBL) or CBL derivative concentrations are disclosed herein as are methods of synthesizing CBL and CBL derivative in high-purity form. Relative to conventional methods, the methods of the present disclosure may: (i) be better suited to large-scale conditions in that they do not require dangerous and/or toxic solvents and/or reagents; (ii) be more tolerant of complex starting compositions, such as cannabinoid extracts, isolates and/or distillates; (iii) provide CBL and/or CBL derivative at higher yield; (iv) provide easier methods to purify product mixtures comprising CBL and/or CBL derivative; (v) provide product mixtures that comprise unique ratios of CBL or CBL derivative relative to other cannabinoids; (vi) provide product mixtures with reduced THC concentrations and/or (vii) provide artificial resins having of a mixture cannabinoids that cannot be produced by extracting cannabis plant material.

Das Prinzip der minimalen chemischen Distanz (PMCD)

Die Ableitung der Isoprenregel, der Mechanismus der Umlagerung von Tetrahydrodicyclopentadien zu Adamantan, fuenf Colchicinsynthesen sowie die Synthese von C16-Hexaquinacen, Morphin und Strychnin werden durch das Prinzip der minimalen chemischen Distanz (PMCD) als Optimierungsprobleme formulierbar und zu Fragen, die mit Computern in der Regel in weniger als einer Sekunde loesbar sind.Das Prinzip der minimalen chemischen Distanz beruht auf einer algebraischen Theorie der konstitutionellen Chemie.Das PMCD, ein Korollar des wohlbekannten Prinzips der minimalen Strukturaenderung, ist eine quantitative heuristische Regel, welche bei der computer-unterstuetzten kombinatorischen Loesung einer Vielfalt chemischer Probleme nuetzlich ist.Dazu zaehlen insbesondere die Strukturanalyse, die Untersuchung von Reaktionsmechanismen und die Syntheseplanung.