214153-52-3 Usage
Molecular structure
The compound has a complex structure that includes a pyridine ring, a sulfonamide group, a propyl side chain, a phenylmethylsulfonamide group, and a carboxylic acid group.
Derivative of pyridine
The compound is a derivative of pyridine, which is a heterocyclic aromatic compound.
Propyl side chain
The compound has a propyl side chain attached to the nitrogen atom of the pyridine ring.
Phenylmethylsulfonamide group
The compound contains a phenylmethylsulfonamide group, which is a benzene ring with a sulfonyl group attached to a methyl group.
Carboxylic acid group
The compound has a carboxylic acid group, which gives it acidic properties.
Potential applications
The compound may have potential applications in medicinal chemistry, particularly in the development of new drugs targeting specific biological pathways or receptors.
Biological and pharmacological activities
The precise biological and pharmacological activities of the compound are not well characterized and would require further investigation.
Check Digit Verification of cas no
The CAS Registry Mumber 214153-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,1,5 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 214153-52:
(8*2)+(7*1)+(6*4)+(5*1)+(4*5)+(3*3)+(2*5)+(1*2)=93
93 % 10 = 3
So 214153-52-3 is a valid CAS Registry Number.
214153-52-3Relevant articles and documents
C6 modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption
Isaacs, Richard C. A.,Cutrona, Kellie J.,Newton, Christina L.,Sanderson, Philip E. J.,Solinsky, Mark G.,Baskin, Elizabeth P.,Chen, I-Wu,Cooper, Carolyn M.,Cook, Jacquelynn J.,Gardell, Stephen J.,Lewis, S. Dale,Lucas Jr., Robert J.,Lyle, Elizabeth A.,Lynch Jr., Joseph J.,Naylor-Olsen, Adel M.,Stranieri, Maria T.,Vastag, Kari,Vacca, Joseph P.
, p. 1719 - 1724 (2007/10/03)
1 (L-374,087) is a potent, selective, efficacious, and orally bioavailable thrombin inhibitor that contains a core 3-amino-2-pyridinone moiety. Replacement of the C6 pyridinone metyl group of 1 by a propyl group gave 5 (L-375,052), which retained all the excellent properties of 1, and also yielded higher plasma levels after oral dosing in dogs and rats.
