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2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 215503-93-8 Structure
  • Basic information

    1. Product Name: 2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide
    2. Synonyms:
    3. CAS NO:215503-93-8
    4. Molecular Formula: C12H10N2O3S
    5. Molecular Weight: 262.2844
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 215503-93-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.416g/cm3
    6. Refractive Index: 1.68
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide(215503-93-8)
    11. EPA Substance Registry System: 2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide(215503-93-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 215503-93-8(Hazardous Substances Data)

215503-93-8 Usage

Contains a thiazole ring

A five-membered ring structure with one sulfur atom and one oxygen atom

Contains an acetamide group

A functional group with an amide bond (-CONH2) attached to an acetic acid group (-COCH3)

Contains a formylphenoxy moiety

A phenol group (-OH attached to a benzene ring) with a formyl group (-CHO) attached to the benzene ring

Potential drug candidate

Has various biological and pharmacological activities

Possible antifungal or antimicrobial properties

The presence of the thiazole ring and formylphenoxy moiety may contribute to these properties

Further research needed

To fully understand the properties and potential applications of this chemical compound.

Check Digit Verification of cas no

The CAS Registry Mumber 215503-93-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,5,0 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 215503-93:
(8*2)+(7*1)+(6*5)+(5*5)+(4*0)+(3*3)+(2*9)+(1*3)=108
108 % 10 = 8
So 215503-93-8 is a valid CAS Registry Number.

215503-93-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-formylphenoxy)-N-(1,3-thiazol-2-yl)acetamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:215503-93-8 SDS

215503-93-8Downstream Products

215503-93-8Relevant articles and documents

Synthesis of New Thiazole-Pyridine Hybrids and Their Anticancer Activity

Alnoman, R. B.,Bayazeed, A. A.

, p. 2004 - 2011 (2020)

Abstract: A series of new thiazole incorporated pyridine derivatives containing the phenoxyacetamide moiety as a linking bridge has been synthesized. The synthetic strategy involves condensation of 2-(4-formylphenoxy)-N-(thiazol-2-yl)acetamide with cyanoacetic hydrazide followed by heterocyclization with acetylacetone, treatment of the produced acrylamides with malononitrile and substituted acetophenones, then heating the generated chalcones with mononitrile in acetic acid and ammonium acetate. In vitro anticancer activity of the newly synthesized thiazole-pyridine hybrids has been evaluated against prostate (PC3), liver (HepG2), laryngeal (Hep-2), and breast (MCF-7) cancer cell lines. One of thiazole-pyridine compounds 8c demonstrates higher activity (IC50 5.71 μM) against breast cancer than 5-fluorouracil used as a reference (IC50 6.14 μM). Molecular docking procedure has provided valuable information on the binding sites of the synthesized compounds with rho-associated protein kinase 1 (ROCK-1).

2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY

-

Page/Page column 73-74; 121, (2016/09/22)

A compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.

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