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6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE is a brominated derivative of tetrahydroisoquinoline, a class of organic compounds found in various natural products. With the molecular formula C9H10BrN·HCl, this chemical compound is known for its potential pharmacological properties and is commonly used in medicinal chemistry. The hydrochloride salt form enhances its stability and solubility in water, making it suitable for various applications.

215798-19-9

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215798-19-9 Usage

Uses

Used in Pharmaceutical Industry:
6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE is used as a therapeutic agent for its potential in treating neurological and psychiatric disorders. Its unique structure and properties allow it to modulate various biological pathways and target specific receptors, offering new avenues for the development of novel treatments.
Used as a Precursor in Synthesis:
In the pharmaceutical industry, 6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE serves as a precursor in the synthesis of other pharmaceutical compounds. Its versatile chemical structure allows for the creation of new molecules with potential therapeutic applications, contributing to the discovery and development of innovative drugs.
Used in Medicinal Chemistry Research:
6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE is utilized as a research tool in medicinal chemistry to explore its pharmacological properties and potential applications. Its unique structure and reactivity make it an interesting candidate for studying various biological interactions and mechanisms, furthering our understanding of its therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 215798-19-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,5,7,9 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 215798-19:
(8*2)+(7*1)+(6*5)+(5*7)+(4*9)+(3*8)+(2*1)+(1*9)=159
159 % 10 = 9
So 215798-19-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H10BrN.ClH/c10-9-2-1-8-6-11-4-3-7(8)5-9;/h1-2,5,11H,3-4,6H2;1H

215798-19-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-bromo-1,2,3,4-tetrahydroisoquinoline,hydrochloride

1.2 Other means of identification

Product number -
Other names 6-BROMO-1,2,3,4-TETRAHYDROISOQUINOLINE HCL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:215798-19-9 SDS

215798-19-9Downstream Products

215798-19-9Relevant articles and documents

RESORCINOL DERIVATIVE AS HSP90 INHIBITOR

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Paragraph 0131, (2017/12/27)

The present invention relates to a compound represented by formula (I) of a resorcinol derivative as an HSP90 inhibitor or pharmaceutically accepted salts thereof. The compound in the present invention has the activity of inhibiting heat shock protein HSP90. Therefore, the compound in the present invention is used to treat proliferative diseases such as cancer and neurodegenerative diseases. The present invention further provides the compounds and preparation methods for pharmaceutical compositions comprising the compounds, a method for treating diseases, and pharmaceutical compositions comprising the compounds.

A practical procedure for reduction of primary, secondary and tertiary amides to amines

Reeves, Jonathan T.,Tan, Zhulin,Marsini, Maurice A.,Han, Zhengxu S.,Xu, Yibo,Reeves, Diana C.,Lee, Heewon,Lu, Bruce Z.,Senanayake, Chris H.

supporting information, p. 47 - 52 (2013/03/13)

A mild and general procedure for reduction of primary, secondary, and tertiary amides using catalytic triruthenium dodecacarbonyl and 1,1,3,3-tetramethyldisiloxane as reductant is described. The reaction is tolerant of numerous functional groups, and the amine products can often be isolated by direct crystallization as hydrochloride salts. The catalyst and silane are commercially available, air stable, and inexpensive, making the procedure accessible for both laboratory and large-scale applications. Copyright

Convenient Synthesis of 6-Bromo-1,2,3,4-tetrahydroisoquinoline and 3-Methoxy-1,2,3,4-tetrahydro-[2,7]-naphthyridine via Reductive Amination of Schiff's Bases

Zlatoidsky, Pavol,Gabos, Balint

experimental part, p. 3060 - 3068 (2009/11/30)

Synthesis of 7-bromo-1,2,3,4-tetrahydroisoquinoline and 6-methoxy-1,2,3,4-tetrahydro-[2,7]-naphthyridine via lithiation of 2-methylarylidene-tert-butylamines, followed by formylation, reductive amination in one-pot, and removal of the tert-butyl group fro

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