2163-11-3Relevant articles and documents
Formation of mono- and di-nuclear complexes of Zn2+ from a 26 membered tetraester crown of 3,5-disubstituted pyrazole able to act as neutral and dianionic ligand
Acerete, Carmen,Bueno, Jose M.,Campayo, Lucrecia,Navarro, Pilar,Isabel Rodriguez-Franco,Samat, Andre
, p. 4765 - 4774 (1994)
A selective synthesis of bis(3,5-diketo-1H-pyrazole)-[26]crown- 12 (1, L1) has been performed. Its deprotonation pKa values, and those of the acyclic analogues (3-5) have been measured. The disodium dipyrazolate salt of 1 (2, [L2]2- 2Na+) has been isolated, and mono- and di- nuclear complexes of Zn2+ obtained from 1 ([L1Zn]2+) and 2 ([L2Zn2]2+) have been studied by 13C NMR spectroscopy in DMSO-d6 solution.
Synthesis and assembly of novel poly(organophosphazene) structures based on noncovalent "host-guest" inclusion complexation
Tian, Zhicheng,Chen, Chen,Allcock, Harry R.
, p. 1065 - 1072 (2014)
The design and assembly of new organophosphazene polymeric materials based on supramolecular "host-guest" interactions was accomplished by linkage of supramolecular coupling units to either the main-chain terminus or the side-chains of the parent phosphazene polymer. Noncovalent interactions at the main chain terminus were used to produce amphiphilic palm-Tree like pseudoblock copolymers via host-guest interactions between an adamantane end-functionalized polyphosphazene and a 4-armed β-cyclodextrin (β-CD) initiated poly[poly(ethylene glycol) methyl ether methacylate] branched-star type polymer. Moreover, noncovalent interactions involving polymer side-chains were achieved between polyphosphazenes with β-CD pendant units and other polyphosphazene molecules with adamantyl moieties on the side-chains. These new organo-phosphazene structures based on noncovalent "host-guest" interactions generate new opportunities for the macromolecular modification of polyphosphazenes. The resultant materials demonstrated useful properties including self-aggregation, supramolecular gelation, and stimulus-responsive behavior.
PYRROLO[2,3-B]PYRIDIN DERIVATIVES AS INHIBITORS OF INFLUENZA VIRUS REPLICATION
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Paragraph 00271, (2020/02/16)
Provided herein are compounds of Formula A, B or C that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza.
DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER
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Paragraph 0078; 0079; 0080, (2016/09/26)
The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH2)n—, —O(CH2)nOC2H4—, —CH2O(CH2)n—, or —CH2O(CH2)nOC2H4—, n represents an integer of 1 to 5, and Q1 represents F or —OCH3.)
P-stereogenic diphosphacrowns: Facile incorporation of aromatic rings
Kato, Ryosuke,Watanabe, Hiroyuki,Morisaki, Yasuhiro,Chujo, Yoshiki
, (2016/03/01)
P-Stereogenic diphosphacrowns containing naphthalene and pyridine rings were synthesized. Facile incorporation of aromatic rings, and chains of different lengths, into the diphosphacrown skeleton was achieved by altering the electrophile in our previously