217090-24-9

Basic information

• Product Name: N-tert-Butyl-4-(2,5-dichloro-pyridin-3-yl)-benzenesulfonamide
• Synonyms: N-tert-Butyl-4-(2,5-dichloro-pyridin-3-yl)-benzenesulfonamide
• CAS NO: 217090-24-9
• Molecular Weight: 359.276
• Mol File: 217090-24-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-tert-Butyl-4-(2,5-dichloro-pyridin-3-yl)-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-tert-Butyl-4-(2,5-dichloro-pyridin-3-yl)-benzenesulfonamide(217090-24-9)
• EPA Substance Registry System: N-tert-Butyl-4-(2,5-dichloro-pyridin-3-yl)-benzenesulfonamide(217090-24-9)

Safety Data

• Hazardous Substances Data: 217090-24-9(Hazardous Substances Data)

Upstream product

• 138006-41-4 3-bromo-2,5-dichloropyridine 
• 208516-15-8 4-(tert-butylaminosulphonyl)benzeneboronic acid 
• 137628-16-1 3-bromo-5-chloro-2-hydroxypyridine 
• 4214-79-3 5-chloro-2-pyridinol 

Relevant articles and documents

2-pyridinyl-3(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors

A series of novel 2-pyridinyl-3-(4-methylsulfonyl)phenylpyridines has been synthesized and evaluated with respect to their ability to inhibit the isozymes of cyclooxygenase, COX-1, and COX-2. Optimum COX-2 activity is observed by introduction of a substituent at C5 of the central pyridine. 5- Chloro-3-(4-methylsulfonyl)phenyl-2(2-methyl-5-pyridinyl)pyridine 33 was identified as the optimum compound in this series.