21712-76-5

Basic information

• Product Name: 2-tert-butoxy-4,6-di-tert-butylphenol
• Synonyms: 2-tert-butoxy-4,6-di-tert-butylphenol
• CAS NO: 21712-76-5
• Molecular Weight: 278.435
• Mol File: 21712-76-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-tert-butoxy-4,6-di-tert-butylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butoxy-4,6-di-tert-butylphenol(21712-76-5)
• EPA Substance Registry System: 2-tert-butoxy-4,6-di-tert-butylphenol(21712-76-5)

Safety Data

• Hazardous Substances Data: 21712-76-5(Hazardous Substances Data)

Upstream product

• 120-80-9 benzene-1,2-diol 
• 115-11-7 isobutene 
• 1020-31-1 3,5-Di-tert-butylcatechol 

Downstream Products

• 13529-38-9 2-tert-Butoxy-4,6-di-tert-butyl-phenoxyl 

Relevant articles and documents

Synthesis and use of ortho-(branched alkoxy)-tert-butoxybenzenes

A series of sterically hindered o-(branched alkoxy)-tert-butoxybenzenes was efficiently prepared in good yields owing to a new practical and simple preparation of o-tert-butoxyphenol starting from catechol and isobutene. Use of DMF di-tert-butyl acetal reagent instead of isobutene/H2SO 4 (cat.) for O-tert-butylation was very convenient in case of ortho bulky phenols affording the corresponding tert-butyl ethers in high yield and purity. This general route proved to be useful since no reliable access was available to o-di-t-BuO-substituted arenes. Application to the synthesis of congested phosphorus-based compounds is presented.