2176-62-7Relevant articles and documents
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Sartori,Adelt
, p. 275,276 (1973)
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Synthesis and crystal structure of 3,5-dichloro-6-morpholinopyridin-2-ol
Zheng, Hui,Liu, Yun-Kui,Shen, Chao,Xu, Zhen-Yuan
, p. 919 - 922 (2009)
A new compound having potential bioactivities 3,5-dichloro-6- morpholinopyridin-2-ol (1) was synthesized and characterized by single crystal X-diffraction. The crystal is monoclinic, space group P21/c with a = 10.3609 (6), b = 10.5711 (7), c = 10.3190 (5) A, β = 108.9433 (15)°, V = 1068.99 (11) A3, Z = 4, C9H 10Cl2N2O2, D c = 1.548 g/cm3, μ (MoKα) = 0.71075 A, S = 1.01, F (000) = 512.00, R = 0.0397 and wR = 0.1364. In the unit cell, there are two independent molecules linked by intermolecular O-H???O (2.693(2) A) hydrogen bonds forming onedimensional expanded structure. Graphical Abstract: As part of our ongoing research work on pyridine derivatives, the title compound crystal structure is important to study the relationship between the structure and its biological activities, thus it is urgent to publish in time.[Figure not available: see fulltext.]
Mild electrophilic halogenation of chloropyridines using CCl4 or C2Cl6 under basic phase transfer conditions
Joshi, Ashutosh V.,Baidossi, Mubeen,Qafisheh, Nida,Chachashvili, Elsa,Sasson, Yoel
, p. 5061 - 5063 (2007/10/03)
Effective chlorination of 2,3,5,6-tetrachloropyridine to pentachloropyridine was realized under mild phase transfer conditions with carbon tetrachloride and 50% NaOH or solid K3PO4. Mechanistic study of this reaction indicated the possibility of an aromatic carbanionic intermediate. Hexachloroethane was established as a more selective electrophilic chlorination agent.
Thermolysis of phenoxyaluminum compounds and formation of PCDD/F and their precursors
Voncina,Medved,Zerjal
, p. 2029 - 2038 (2007/10/03)
Within the study of the formation of chlorinated dioxins and dibenzofurans and their precursors the thermolysis of hexachloroethane over the aluminum melt was investigated. "De novo" synthesis of precursors of PCDD/F was studied in the model system AlCl3/elemental carbon. Totally chlorinated heterocyclic compounds have been detected parallel with the formation of organochlorine compounds. The possibility of inserting oxygen to aluminum organyls was presented. In order to gain more detailed knowledge of the catalytic behaviour of fly ash the chemistry of thermolysis of phenoxy- and chlorophenoxy aluminum compounds at 300°C with the presence and absence of Al2O3 was investigated. Reagent compounds and products of thermolysis were followed by mass spectrometry.