2177-97-1

Basic information

• Product Name: 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol
• Synonyms: 1,2,3-Propanetriyl=1,3-dipalmitate 2-stearate;1,3-Dipalmito-2-stearin;1,3-Dipalmitoyl-2-stearin;1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol;2-O-Stearoyl-1-O,3-O-bispalmitoylglycerol;2-Stearo-1,3-dipalmitin
• CAS NO: 2177-97-1
• Molecular Formula: C₅₃H₁₀₂O₆
• Molecular Weight: 835.37
• Mol File: 2177-97-1.mol

Chemical Properties

• Melting Point: 59.5 °C
• Boiling Point: 777.9±27.0 °C(Predicted)
• Appearance: /
• Density: 0.913±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol(2177-97-1)
• EPA Substance Registry System: 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol(2177-97-1)

Safety Data

• Hazardous Substances Data: 2177-97-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol is used as a component in the formulation of lipid-based drug delivery systems for enhancing the solubility, stability, and bioavailability of lipophilic drugs. Its unique fatty acid composition provides advantages in terms of controlled release and targeted drug delivery.
Used in Nutritional Research:
In the field of nutritional science, 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol is utilized as a model compound to study the effects of dietary fat intake on energy metabolism and body weight regulation. The observation of its levels in rats with reduced food intake-induced energy depletion provides insights into the role of triacylglycerols in energy balance and metabolism.
Used in Cosmetics Industry:
1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol is employed as an ingredient in the cosmetics industry, particularly in the formulation of creams and lotions. Its emollient properties help to moisturize and protect the skin, while its stability contributes to the shelf life of cosmetic products.
Used in Food Industry:
In the food industry, 1-O,3-O-Dipalmitoyl-2-O-stearoyl-L-glycerol is used as an additive to improve the texture, mouthfeel, and stability of various food products. Its unique fatty acid composition may also play a role in the development of reduced-calorie or healthier food options by influencing the digestibility and absorption of fats.

Upstream product

• 2190-25-2 2-Oleodipalmitin 
• 57-11-4 stearic acid 
• 112-76-5 Stearoyl chloride 
• 555-44-2 glyceroltripalmitate 
• 51621-38-6 2-stearoyloxy-1,3-bis-trityloxy-propane 
• 112-67-4 n-hexadecanoyl chloride 

Relevant articles and documents

Interesterification Kinetics of Triglycerides and Fatty Acids with Modified Lipase in n-Hexane

The kinetics of lipase-catalyzed interesterification of triglycerides and fatty acids in organic media was studied.First, the lipase Saiken 100, Rhizopus japonicus, was modified by surfactant to form an enzyme precipitate in aqueous solution, which was well dispersed in organic solvents.This modified lipase catalyzed the interesterification of tripalmitin and stearic acid.The enzyme has 1,3-positional specificity and does not distinguish between stearic and palmitic acids.The kinetic model developed to describe the interesterification reaction system is based on mass balance of two consecutive second-order reversible reactions.The reaction rate constant, k, was determined by solving the differential rate equations of the reaction system and by expressing the value of k as a function of concentrations of the substrates with time.The model gave satisfactory results.The best value of the specific reaction rate constant k* that fits all experimental data was 1.2*10-5 2/(mmol*mg biocatalyst*h)> under the reaction conditions in this study. Key words: Acidolysis, biocatalyst, fatty acids, interesterification kinetics, modified lipase, palmitic acid, reaction rate constant, stearic acid, triglycerides.