21896-59-3

Basic information

• Product Name: N-(2-chloroethyl)methanesulphonamide
• Synonyms: N-(2-chloroethyl)methanesulphonamide;Einecs 244-641-6
• CAS NO: 21896-59-3
• Molecular Formula: C₃H₈ClNO₂S
• Molecular Weight: 157.61912
• EINECS: 244-641-6
• Mol File: 21896-59-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 245.8 °C at 760 mmHg
• Flash Point: 102.5 °C
• Appearance: /
• Density: 1.321 g/cm³
• Vapor Pressure: 0.0281mmHg at 25°C
• Refractive Index: 1.469
• Storage Temp.: Room temperature.
• CAS DataBase Reference: N-(2-chloroethyl)methanesulphonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloroethyl)methanesulphonamide(21896-59-3)
• EPA Substance Registry System: N-(2-chloroethyl)methanesulphonamide(21896-59-3)

Safety Data

• Hazardous Substances Data: 21896-59-3(Hazardous Substances Data)

Usage

Uses

N-(2-Chloroethyl)methanesulfonamide

InChI:InChI=1/C3H8ClNO2S/c1-8(6,7)5-3-2-4/h5H,2-3H2,1H3

Upstream product

• 107-06-2 1,2-dichloro-ethane 
• 689-98-5 chloroethylamine 
• 870-24-6 2-chloroethanamine hydrochloride 
• 124-63-0 methanesulfonyl chloride 
• 151-56-4 ethyleneimine 

Downstream Products

• 92-09-1 N-{2-[(4-amino-m-tolyl)ethylamino]ethyl}methanesulfonamide 
• 56891-61-3 4-acetamino-3-methyl-N-(β-methanesulfonamidoethyl)-N-ethylaniline 

Relevant articles and documents

Practical Synthesis of Sultams via Sulfonamide Dianion Alkylation: Application to the Synthesis of Chiral Sultams

(Equation presented) A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.

Method for production of N-(2-chloroethyl) methanesulfonamide

A method for the production of N-(2-chloroethyl) methanesulfonamide of high purity, which method comprises causing methanesulfonyl chloride to react with ethylene imine in the presence of ethylene dichloride and then distilling there resultant reaction mixture thereby separating therefrom N-(2-chloroethyl) methanesulfonamide, if necessary subjecting the resultant reaction mixture to extraction from water, separating the aqueous layer consequently formed, and subjecting the organic layer resulting from said extraction to distillation thereby separating N-(2-chloroetyl) methanesulfonamide.