21921-76-6 Usage
Uses
Used in Pharmaceutical Industry:
4-Bromo-2-furaldehyde is used as a key building block for the synthesis of furanyl cyclobutenediones, which are potent G-protein coupled receptor (GPCR) antagonists. These antagonists play a crucial role in the development of novel therapeutic agents targeting a wide range of diseases, including neurological disorders, cardiovascular conditions, and various forms of cancer. The unique structure of 4-Bromo-2-furaldehyde allows for the efficient synthesis of these bioactive molecules, contributing to the advancement of pharmaceutical research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 21921-76-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,2 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21921-76:
(7*2)+(6*1)+(5*9)+(4*2)+(3*1)+(2*7)+(1*6)=96
96 % 10 = 6
So 21921-76-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H3BrO2/c6-4-1-5(2-7)8-3-4/h1-3H
21921-76-6Relevant articles and documents
Synthesis of 5-bromo-2-furfural under solvent-free conditions using 1-butyl-3-methylimidazolium tribromide as brominating agent
Wu, Xiangrui,Peng, Xinhua,Dong, Xiongzi,Dai, Zhihong
experimental part, p. 927 - 928 (2012/07/30)
The development of a facile and general method for the preparation of 5-bromo-2-furfural is described. An excellent yield of high regioselectivity came out of the bromination reaction of 2-furfural with 1-butyl-3- methylimidazolium tribromide under solvent-free conditions.
