219739-90-9Relevant articles and documents
Syntheses of 5-amino-2-phenyl-4(3H)-pyrimidinone derivertives starting with glycine
Takahashi, Daisuke,Honda, Yutaka,Izawa, Kunisuke
scheme or table, p. 1089 - 1103 (2012/08/07)
N-Cbz derivative of 5-amino-2-phenyl-4(3H)-pyrimidinone was prepared from sodium salt of methyl hydroxymethylene glycinate and benzamidine hydrochloride in good yield. However, the reaction with N-substituted benzamidine did not proceed to give the desired pyrimidinone. In contrast, the reaction of 4-ethoxymethylene-2-phenyl-5(4H)-oxazolone readily prepared from hippuric acid and N-substituted benzamidine proceeded nicely to give 5-(benzoylamino)-6-oxo-2- phenyl-1(6H)-pyrimidineacetic acid in high yield.
Synthesis and characterisation of some new N-glycosides containing substituted pyridopyrimidinone, pyrimidopyridazinone, thiazolopyrimidinone and quinolizin-4-one moiety
Simunek, Petr,Svete, Jurij,Stanovnik, Branko
experimental part, p. 2477 - 2491 (2011/04/17)
A series of new N-glycosides (D-glucosides, D-mannosides, L-and D-arabinosides, D-xylosides and one D-galactoside) containing heterocyclic moiety have been prepared by reaction of the corresponding heterocyclic amines with pyranoses in boiling methanol. The structures of the prepared compounds have been studied by means of proton and carbon NMR spectroscopy. In the most cases the products existed in DMSO solution as the single anomers. The Japan Institute of Heterocyclic Chemistry.
