220158-68-9Relevant articles and documents
HETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDIATORS OF STEAROYL-COA DESATURASE
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Page/Page column 45, (2010/10/20)
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): Formula (I) where x, y, G, J, L, M, V, W, R2, R3, R4, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Special 3-azabicyclo[3.1.0]hexanes, method for producing and modifying the same, and their use
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, (2008/06/13)
6-Amino-3-azabicyclo[3.1.0]hexanes of the formula wherein R1and R2independently of one another are C3-C4-alkenyl or Ar—CH(R′)— where R′ is hydrogen or C1-C4-alkyl and Ar is an optionally substituted C6-C10-aryl and R3is hydrogen, C3-C4-alkenyl, Ar—CH(R′)— where R′ is hydrogen or C1-C4-alkyl and Ar is an optionally substituted C6-C10-aryl or COOR4where R4is C1-C4-alkyl or C2-C4-alkenyl. The invention also relates to a method for making these compounds and a method for using them.