221025-36-1

Basic information

• Product Name: N-(p-methoxybenzyl)-quinoxalin-2-one
• Synonyms: N-(p-methoxybenzyl)-quinoxalin-2-one
• CAS NO: 221025-36-1
• Molecular Weight: 266.299
• Mol File: 221025-36-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-(p-methoxybenzyl)-quinoxalin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-methoxybenzyl)-quinoxalin-2-one(221025-36-1)
• EPA Substance Registry System: N-(p-methoxybenzyl)-quinoxalin-2-one(221025-36-1)

Safety Data

• Hazardous Substances Data: 221025-36-1(Hazardous Substances Data)

Upstream product

• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 2746-25-0 p-Methoxybenzyl bromide 
• 95-54-5 1,2-diamino-benzene 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 221067-99-8 1-[(4-Methoxyphenyl)methyl]-7-nitro-2(1H)-quinoxalinone 
• 179042-26-3 imidazo[1,5-a]quinoxalin-6(5H)-one 
• 221025-37-2 5-(4-methoxybenzyl)imidazo[1,5-a]quinoxalin-4(5H)-one 

Relevant articles and documents

Metal-Free Direct Oxidative C?N Bond Coupling of Quinoxalin-2(1H)-ones with Azoles under Mild Conditions

Direct C3?H amination of quinoxalin-2(1H)-ones with azoles under mild conditions promoted by PIFA has been achieved in good yield in a very fast manner. Mechanistic study revealed that the reaction proceeds through a radical process. In addition, this method could be applied to gram-scale reaction.

Electrochemical Cross-Coupling of C(sp2)?H with Aryldiazonium Salts via a Paired Electrolysis: an Alternative to Visible Light Photoredox-Based Approach

Photoredox-based C?H bond functionalization constitutes one of the most powerful and atom-economical approaches to organic syntheses. During this type of reaction, single electron transfer takes place between the photocatalyst (PC) and redox- active substrates. Electrosynthesis also involves electron transfer between substrates and electrodes. In this paper, we focus upon electrochemical cross-coupling of C(sp2)?H with aryldiazonium salts and have developed an efficient electrochemical approach to the Minisci-type arylation reaction. The constant current paired electrosynthesis proceeds in a simple undivided cell without external supporting electrolyte, features a wide range of substrates and is easy to scale-up. These results demonstrate that photoredox-based cross-coupling of C(sp2)?H with aryldiazonium salts can also proceed successfully under paired electrolysis conditions, thereby contributing to understanding of the parallels between photosynthesis and electrosynthesis. (Figure presented.).

Imidazoquinoxaline protein tyrosine kinase inhibitors

Novel imidazoquinoxalines and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders.