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221174-22-7

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221174-22-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 221174-22-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,7 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 221174-22:
(8*2)+(7*2)+(6*1)+(5*1)+(4*7)+(3*4)+(2*2)+(1*2)=87
87 % 10 = 7
So 221174-22-7 is a valid CAS Registry Number.

221174-22-7Relevant articles and documents

HOAt.DCHA as co-coupling agent in the synthesis of peptides employing Fmoc-amino acid chlorides as coupling agents: Application to the synthesis of ss-casomorphin

Sureshbabu, Vommina V.,Chennakrishnareddy, Gundala

experimental part, p. 981 - 988 (2009/12/28)

A simple, efficient and racemization free method for the synthesis of peptides employing Fmoc-amino acid chlorides mediated by HOAtDCHA as a co-coupling agent has been described. This protocol is successfully employed in the synthesis of the pentapeptide H-Pro-Gly-VaI-GIy-VaI-OH (PGVGV), and ss-casomorphin (H-Tyr-Pro-Phe-Pro-Gly-OH) in 85 and 80% yields, respectively.

Fmoc-peptide acid chlorides in fragment coupling: Synthesis of β- casomorphin by 3+2 divergent approach

Suresh Babu,Gayathri,Gopi

, p. 79 - 91 (2007/10/03)

Fmoc-peptide acid chlorides are prepared and used as rapid and efficient coupling agents in fragment coupling. Thus the synthesis of the model tetrapeptide Leu-Ala-Gly-Val and β-casomorhin (Tyr-Pro-Phe-Pro-Gly) are accomplished by the (2+2) and (3+2) divergent approach respectively.

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