221194-62-3

Basic information

• Product Name: (3-chloropropoxy)cyclohexane
• Synonyms: (3-chloropropoxy)cyclohexane
• CAS NO: 221194-62-3
• Molecular Formula: C₉H₁₇ClO
• Molecular Weight: 176.69
• Mol File: 221194-62-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-chloropropoxy)cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: (3-chloropropoxy)cyclohexane(221194-62-3)
• EPA Substance Registry System: (3-chloropropoxy)cyclohexane(221194-62-3)

Safety Data

• Hazardous Substances Data: 221194-62-3(Hazardous Substances Data)

Usage

General Description

"(3-chloropropoxy)cyclohexane" is a chemical compound with the molecular formula C9H17ClO. It is a cyclohexane derivative with a chlorine atom attached to a three-carbon chain that is in turn bonded to the cyclohexane ring. This chemical is widely used as a solvent in various industrial applications, and it is also utilized as a building block in the synthesis of other organic compounds. It can undergo various chemical reactions, such as nucleophilic substitution, oxidation, and reduction, to form different derivatives with diverse chemical properties and applications. Additionally, it is important to handle this compound with caution as it may pose health and environmental risks due to its potential toxicity and ability to pollute air and water.

Upstream product

• 180-93-8 1,5-dioxa-spiro[5.5]undecane 
• 108-93-0 cyclohexanol 
• 75322-09-7 3-cyclohexyloxypropyl alcohol 

Relevant articles and documents

A General Approach to Deboronative Radical Chain Reactions with Pinacol Alkylboronic Esters

The generation of carbon-centered radicals from air-sensitive organoboron compounds through nucleohomolytic substitution at boron is a general method to generate non-functionalized and functionalized radicals. Due to their reduced Lewis acidity, alkylboronic pinacol esters are not suitable substrates. We report their in situ conversion into alkylboronic catechol esters by boron-transesterification with a substoichiometric amount of catechol methyl borate combined with an array of radical chain processes. This simple one-pot radical-chain deboronative method enables the conversion of pinacol boronic esters into iodides, bromides, chlorides, and thioethers. The process is also suitable the formation of nitriles and allylated compounds through C?C bond formation using sulfonyl radical traps. The power of combining radical and classical boron chemistry is illustrated with a modular 5-membered ring formation using a combination of three-component coupling and protodeboronative cyclization.