22201-45-2

Basic information

• Product Name: 4-TERT-BUTYLBENZOIC ANHYDRIDE
• Synonyms: 4-TERT-BUTYLBENZOIC ANHYDRIDE
• CAS NO: 22201-45-2
• Molecular Formula: C₂₂H₂₆O₃
• Molecular Weight: 0
• Mol File: 22201-45-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 75-81℃
• Boiling Point: 455.326°C at 760 mmHg
• Flash Point: 209.023°C
• Appearance: /
• Density: 1.057g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.536
• CAS DataBase Reference: 4-TERT-BUTYLBENZOIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYLBENZOIC ANHYDRIDE(22201-45-2)
• EPA Substance Registry System: 4-TERT-BUTYLBENZOIC ANHYDRIDE(22201-45-2)

Safety Data

• Hazardous Substances Data: 22201-45-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H26O3/c1-21(2,3)17-11-7-15(8-12-17)19(23)25-20(24)16-9-13-18(14-10-16)22(4,5)6/h7-14H,1-6H3

Upstream product

• 108-24-7 acetic anhydride 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 877-65-6 p-tert-butylbenzyl alcohol 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 939-97-9 4-tert-Butylbenzaldehyde 
• 201230-82-2 carbon monoxide 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 615-36-1 2-bromoaniline 

Downstream Products

• 1380434-18-3 (4-(tert-butyl)phenyl)(1-tosylpiperidin-4-yl)methanone 
• 28047-27-0 (4-(tert-butyl)phenyl)(cyclohexyl)methanone 
• 1017160-42-7 (4-(tert-butyl)phenyl)(cyclopentyl)methanone 
• 1380434-51-4 1-(4-tert-butylphenyl)-2-(trimethylsilyl)ethanone 
• 1384969-52-1 2-(4-(4-(tert-butyl)phenyl)-3-methyl-4-oxobutyl)isoindoline-1,3-dione 
• 914220-77-2 1-(4-(tert-butyl)phenyl)pentan-1-one 
• 1384969-49-6 piperidine-1,4-diylbis((4-(tert-butyl)phenyl)methanone) 
• 1384969-44-1 4-(4-(tert-butyl)phenyl)-3-methyl-4-oxobutyl 2-methoxybenzoate 
• 1380434-49-0 4-(4-(tert-butyl)phenyl)-3-methyl-4-oxobutyl 4-cyanobenzoate 
• 1384969-46-3 4-(4-(tert-butyl)phenyl)-4-oxobutyl 4-methoxybenzoate 
• 1380434-50-3 1-(4-tert-butylphenyl)-3,3-dimethoxypropan-1-one 
• 60561-82-2 1-(4-(tert-butyl)phenyl)-2-methylpropan-1-one 
• 1178005-94-1 C₂₀H₁₈O₄ 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 

Relevant articles and documents

Metal-free oxidative self-coupling of aldehydes or alcohols to symmetric carboxylic anhydrides

A metal-free synthesis of symmetrical anhydrides has been developed starting from aldehydes, both aliphatic and aromatic or primary benzylic alcohols. The reaction occurs at room temperature and makes use of trichloroisocyanuric acid (TCCA) as an oxidant providing the desired carboxylic anhydrides in satisfactory yields.

Oxidative self-coupling of aldehydes in the presence of CuCl2/TBHP system: Direct access to symmetrical anhydrides

A simple synthesis of symmetrical anhydrides has been developed. Using tert-butylhydroperoxide (TBHP) as the oxidant and copper(II) chloride as the catalyst in acetonitrile, various aromatic and heteroaromatic aldehydes were reacted to provide symmetrical anhydrides in modest to good yields.

Carboxylic acid anhydrides via Pd-catalyzed carbonylation of aryl halides at atmospheric CO pressure

A convenient method has been developed, which allows for the direct transformation of aryl iodides into the corresponding carboxylic acid anhydrides via Pd-catalyzed carbonylation under atmospheric CO pressure. The Royal Society of Chemistry 2012.