22251-34-9

Basic information

• Product Name: (methoxymethoxy)ethane
• Synonyms: (Methoxymethoxy)ethane; ethane, (methoxymethoxy)-; ethoxymethoxymethane
• CAS NO: 22251-34-9
• Molecular Formula: C₄H₁₀O₂
• Molecular Weight: 90.121
• Mol File: 22251-34-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 70.4°C at 760 mmHg
• Density: 0.839g/cm³
• Vapor Pressure: 140mmHg at 25°C
• Refractive Index: 1.366
• CAS DataBase Reference: (methoxymethoxy)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: (methoxymethoxy)ethane(22251-34-9)
• EPA Substance Registry System: (methoxymethoxy)ethane(22251-34-9)

Safety Data

• Hazardous Substances Data: 22251-34-9(Hazardous Substances Data)

Usage

General Description

(Methoxymethoxy)ethane, also known as triethylene glycol dimethyl ether, is a colorless, flammable liquid with a faint odor. It is commonly used as a solvent in chemical and pharmaceutical industries, as well as in the production of plastics and other materials. It has a high boiling point and low volatility, making it a suitable solvent for high-temperature processes. It also has a low viscosity and good solubility in water, making it an effective component in hydraulic fluids and other industrial applications. However, it can be a potential health and environmental hazard if not handled and disposed of properly, so precautions should be taken when using (methoxymethoxy)ethane in industrial settings.

Upstream product

• 67-56-1 methanol 
• 50-00-0 formaldehyd 
• 64-17-5 ethanol 
• 109-87-5 Dimethoxymethane 
• 56-23-5 tetrachloromethane 
• 462-95-3 formaldehyde diethyl acetal 
• 105-57-7 diethyl acetal 
• 25289-73-0 methoxymethyl methanesulfonate 
• 141-52-6 sodium ethanolate 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 101415-97-8 (2RS,5RS,9SR,10RS)-9-methoxymethoxy-6,10-dimethyl-2-pivaloyloxyspiro<4.5>dec-6-en-8-one 
• 101467-36-1 (2RS,5RS,8SR,9SR,10RS)-8,9-bis(methoxymethoxy)-6,10-dimethyl-2-pivaloyloxyspiro<4.5>dec-6-ene 

Relevant articles and documents

Acetal Metathesis: Mechanistic Insight

The origins and recent applications of acetal metathesis are discussed in the context of synthesizing polyacetals via acetal metathesis polymerization (AMP). A kinetic study of the acid-catalyzed acetal metathesis reaction suggests the rate = k [H + ][acetal] 2, with MeOCH 2 OMe and EtOCH 2 OEt interchanging to yield MeOCH 2 OEt, achieving the statistical 1:2:1 equilibrium distribution in 4 hours at 80 °C and in 1 hour at 90 °C. Upon heating 1,10-decanediol and diethoxymethane, polydecylene acetal is formed with sequential distillation of ethanol, followed by diethoxymethane. A full mechanism for this polymerization is proposed, which begins with a transacetalization sequence to convert the diol into a bisacetal, followed by acetal metathesis to yield a high-molecular-weight polymer.

Method for preparing ethoxy methoxymethane

The invention provides a method for preparing ethoxy methoxymethane, and relates to a chemical reagent preparation method. According to the method, dimethoxymethane and ethanol serving as raw materials are used to prepare the ethoxy methoxymethane at certain temperature and pressure by using liquid acid and loaded solid acid as catalysts, wherein the liquid acid catalyst is one or more of inorganic acids including sulfuric acid, hydrochloric acid, nitric acid and hydrofluoric acid; the mass percentage of the sulfuric acid catalyst is 0-98 percent, the hydrochloric acid catalyst is an aqueous solution containing hydrogen chloride having a concentration of 0-38 percent, the mass percentage of the nitric acid catalyst is 0-95 percent, and the mass percentage of the hydrofluoric acid catalyst is 0-55 percent; the reaction is performed at the temperature of 0-160 DEG C at a pressure of 0.1-10.0MPa; and the filling gas is one or mixed gas of inert gas, argon, helium, carbon dioxide and nitrogen. The method is relatively single in product and high in selectivity and is prepared from low-price and easily-available raw materials; and the whole process is simple in operation, does not generate chemical substances which pollute the environment, and belongs to an environment-friendly process flow.

Preparation method of ethoxymethoxy methane

The invention relates to a method for preparing methane, particularly a method for preparing ethoxymethoxy methane. According to the method, dimethoxymethane and ethanol are used as raw materials to prepare the ethoxymethoxy methane under the conditions of certain temperature and pressure by using a resin as a catalyst. The resin catalyst is one or more of KAD302, KC107, NKC-9, DA-330, D009B, Amberlyst-15 and D072H. The resin catalyst is mainly composed of a sulfo-containing resin catalyst. The reaction temperature is 0-160 DEG C, and the reaction pressure is 0.1-10.0 MPa. The filling gas is inert gas which is argon, helium, carbon dioxide or nitrogen or a gas mixture thereof. The reactor is a fixed-bed or tank reactor. The mole ratio of the raw material dimethoxymethane to the ethanol is 1:2-5:1. The synthesis process has the advantages of simple product, fewer side reactions and high selectivity for the required product ethoxymethoxy methane. The method provided by the invention basically does not pollute the environment.