22329-75-5

Basic information

• Product Name: 2,4-Octadienoic acid, (E,E)-
• Synonyms: octa-2t,4t-dienoic acid;(2E,4E)-2,4-octadienoic acid;(E,E)-2,4-Octadienoic acid;Octa-2t,4t-diensaeure;(2E,4E)-octa-2,4-dienoic acid;2E,4E-octadienoic acid
• CAS NO: 22329-75-5
• Molecular Formula: C8H12O2
• Molecular Weight: 140.182
• Mol File: 22329-75-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2,4-Octadienoic acid, (E,E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Octadienoic acid, (E,E)-(22329-75-5)
• EPA Substance Registry System: 2,4-Octadienoic acid, (E,E)-(22329-75-5)

Safety Data

• Hazardous Substances Data: 22329-75-5(Hazardous Substances Data)

Usage

General Description

2,4-Octadienoic acid, also known as sorbic acid, is a naturally occurring organic compound commonly used as a food preservative due to its ability to inhibit the growth of mold, yeast, and some bacteria. It is classified as a polyunsaturated fatty acid and is commonly found in fruits like berries and apples, as well as in some cheeses. The compound is generally recognized as safe for consumption at low levels, and is listed as an approved food additive by the FDA. In addition to its use as a preservative, 2,4-Octadienoic acid has also been studied for its potential health benefits, including anti-fungal and anti-inflammatory properties.

Upstream product

• 110-86-1 pyridine 
• 6728-26-3 (E)-2-Hexenal 
• 141-82-2 malonic acid 
• 30361-28-5 trans,trans-2,4-octadienal 
• 18776-92-6 (E)-2-(pent-1-en-1-yl)benzoic acid 
• 16400-69-4 6-propyl-5,6-dihydro-2H-pyran-2-one 
• 60388-61-6 ethyl (2E,4E)-octa-2,4-dienoate 
• 75785-78-3 ethyl 3-chlorohexenoate 
• 2305-25-1 3-hydroxy-hexanoic acid ethyl ester 
• 1308312-20-0 3-chlorohexanal 
• 4071-85-6 trimetylsilylketene 

Downstream Products

• 56904-85-9 (E,E)-octa-2,4-dien-1-ol 
• 214827-40-4 (2E,4E)-Octa-2,4-dienoic acid (4S,5S,7R,7aS)-5-(2-benzenesulfonyl-1,1-dimethyl-ethyl)-5-methoxy-2-oxo-7-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-ylmethyl)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-4-yl ester 
• 247146-38-9 C₆₁H₈₂O₁₈ 
• 107-92-6 butyric acid 
• 1409973-08-5 C₂₀H₂₁NO 
• 1409973-25-6 C₃₁H₄₃NOSi 
• 60388-65-0 deca-4t,6t-dienoic acid 
• 220944-28-5 (4R,5S)-4-methyl-5-phenyl-3-((2E,4E)-1-oxo-2,4-octadienyl)-2-oxazolidinone 

Relevant articles and documents

Unsaturated carbonyl compounds and their preparation method and application

The invention discloses a unsaturated carbonyl compounds and their preparation method and application. The unsaturated carbonyl compounds of the general formula as the molecular structure of the following formula (I) as shown: The unsaturated carbonyl com

Synthesis of polymeric ladders by topochemical polymerization

Two polymeric ladders were synthesized by topochemical polymerization. The critical assemblies with multiple reactive centers were characterized by single crystal X-ray diffraction. Approximately 64% and 70% of the mass of the two polymeric ladders can be

Mining the Cinnabaramide Biosynthetic Pathway to Generate Novel Proteasome Inhibitors

The cinnabaramides and salinosporamides are mixed PKS/NRPS natural products isolated from a terrestrial streptomycete and a marine actinomycete, respectively. They interfere with the proteasome and thus potentially inhibit the growth of cancer cells. The compounds exhibit a γ-lactam-β-lactone bicyclic ring structure attached to a cyclohexenyl unit and a PKS side chain. As a first step towards improving anticancer activity and permitting genetic approaches to novel analogues, we have cloned and characterized the cinnabaramide biosynthetic genes from Streptomyces sp. JS360. In addition to the expected PKS and NRPS genes, the cluster encodes functionalities for the assembly of the hexyl side chain precursor. The corresponding enzymes exhibit relaxed substrate specificities towards a number of synthesized precursors, enabling production of novel chlorinated cinnabaramides. These were isolated and analyzed for activity, revealing that derivatives bearing a chlorine atom in the PKS side chain show higher inhibitory potentials towards the proteasome's proteolytic subunits (especially the trypsin and chymotrypsin units) and higher cytotoxicities towards human tumor cell lines than the parent cinnabaramide A. Although their activities towards the proteasome were weaker than that of salinosporamide A, the cinnabaramides were found to inhibit the growth of various fungi with greater potency. Copyright