225217-42-5

Basic information

• Product Name: 4-Methylumbelliferyl2-O-(a-L-fucopyranosyl)-b-D-galactopyranoside
• Synonyms: 4-Methylumbelliferyl 2-O-(α-L-fucopyranosyl)-β-D-galactopyranoside;7-[[2-O-(6-Deoxy-α-L-galactopyranosyl)-β-D-galactopyranosyl]oxy]-4-Methyl-2H-1-benzopyran-2-one;Fuc1-α-2Gal--4Mu;7-[[2-O-(6-Deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one,7-[[2-O-(6-deoxy-a-L-galactopyranosyl)-b-D-galactopyranosyl]oxy]-4-methyl-
• CAS NO: 225217-42-5
• Molecular Formula: C22H28O12
• Molecular Weight: 0
• EINECS: 1533716-785-6
• Product Categories: Fluorescent Labels & Indicators
• Mol File: 225217-42-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Methylumbelliferyl2-O-(a-L-fucopyranosyl)-b-D-galactopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylumbelliferyl2-O-(a-L-fucopyranosyl)-b-D-galactopyranoside(225217-42-5)
• EPA Substance Registry System: 4-Methylumbelliferyl2-O-(a-L-fucopyranosyl)-b-D-galactopyranoside(225217-42-5)

Safety Data

• Hazardous Substances Data: 225217-42-5(Hazardous Substances Data)

Usage

Uses

A synthetic chromogenic substrate for the assay of a-fucosidases.

Upstream product

• 90-33-5 7-hydroxy-4-methyl-chromen-2-one 

Relevant articles and documents

Synthesis of fucosidase substrates using propane-1,3-diyl phosphate as the anomeric leaving group

Activation of the anomeric centre of suitably protected L-fucopyranose and D-galactopyranose with propane-1,3-diyl phosphate allowed the synthesis of the disaccharide α-L-Fucp-(1,2)-β-D-Galp(1)-4-methylumbelliferone as a fucosidase substrate.

Stereoselective synthesis of α-L-Fucp-(1,2)- and -(1,3)-β-D-Galp(1)-4-methylumbelliferone using glycosyl donor substituted by propane-1,3-diyl phosphate as leaving group

Stereoselective synthesis of α-L-Fucp-(1,2)- and -(1,3)-β-D-Galp(1)-4-methyllumbelliferone was accomplished using glycosyl donor substituted by propane-1,3-diyl phosphate as leaving group. The α-stereochemistry for the anomeric centre was assigned on the basis of the observed 13C-H coupling constant of 165.4 Hz for the bond. The results suggested that the bond-forming reaction intermediate was formed through participation of the second carbon acetoxy function or by an SN2-like process.