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(R)-1-(4-chlorobenzyl)-3-(glycylamino)pyrrolidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

226249-02-1

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226249-02-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 226249-02-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,6,2,4 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 226249-02:
(8*2)+(7*2)+(6*6)+(5*2)+(4*4)+(3*9)+(2*0)+(1*2)=121
121 % 10 = 1
So 226249-02-1 is a valid CAS Registry Number.

226249-02-1Relevant articles and documents

Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series

Moree, Wilna J.,Kataoka, Ken-ichiro,Ramirez-Weinhouse, Michele M.,Shiota, Tatsuki,Imai, Minoru,Tsutsumi, Takaharu,Sudo, Masaki,Endo, Noriaki,Muroga, Yumiko,Hada, Takahiko,Fanning, Dewey,Saunders, John,Kato, Yoshinori,Myers, Peter L.,Tarby, Christine M.

, p. 1869 - 1873 (2008/09/19)

SAR studies were conducted around lead compound 1 using high-throughput parallel solution and solid phase synthesis. Our lead optimization efforts led to the identification of several CCR2b antagonists with potent activity in both binding and functional a

Cyclic amine derivatives and their use as drugs

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, (2008/06/13)

A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1α and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atheroclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.

CYCLOAMINE CCR5 RECEPTOR ANTAGONISTS

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, (2008/06/13)

Remedies or prophylactics for diseases in association with CCR5 such as AIDS, rheumatoid arthritis or nephritis comprising a cyclic amine compound represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a phar

CYCLIC AMINE CCR3 ANTAGONISTS

-

, (2008/06/13)

A medicine containing, as an active ingredient, a cyclic amine derivative represented by the following formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1 to C6 alkyl addition sal

REMEDIES OR PREVENTIVES FOR DISEASES IN ASSOCIATION WITH CHEMOKINES

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, (2008/06/13)

This invention provides remedies or prophylactics for diseases in association with chemokines such as MIP-1 α and/or MCP-1. Namely, remedies or prophylactics for diseases in association with the chemokines such as rheumatoid arthritis or nephritis contain

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