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CAS

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227184-11-4

6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is an organic chemical compound with the chemical formula C6H7FN2O. It is a pyrimidinone derivative with a fluorine-containing ethyl group attached to the sixth carbon in the pyrimidinone ring. 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is commonly used in pharmaceutical research and drug development as a building block for the synthesis of various bioactive molecules and pharmaceuticals. Its unique structural features and reactivity make it a valuable intermediate in organic synthesis, particularly in the development of potential drug candidates for various therapeutic applications. Furthermore, its fluorine-containing moiety makes it an important functional group for the development of fluorinated pharmaceuticals, which often exhibit improved properties and biological activity compared to non-fluorinated analogs.

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  • 227184-11-4 Structure

  • Basic information

    1. Product Name: 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE
    2. Synonyms: 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE;4(1H)-Pyrimidinone, 6-(1-fluoroethyl)- (9CI)
    3. CAS NO:227184-11-4
    4. Molecular Formula: C6H7FN2O
    5. Molecular Weight: 142.13
    6. EINECS: N/A
    7. Product Categories: PYRIMIDINE;Pyrimidine series
    8. Mol File: 227184-11-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE(227184-11-4)
    11. EPA Substance Registry System: 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE(227184-11-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 227184-11-4(Hazardous Substances Data)

227184-11-4 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is used as a building block for the synthesis of various bioactive molecules and pharmaceuticals. Its unique structural features and reactivity make it a valuable intermediate in organic synthesis, particularly in the development of potential drug candidates for various therapeutic applications.
Used in the Development of Fluorinated Pharmaceuticals:
6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is used as an important functional group for the development of fluorinated pharmaceuticals. The presence of a fluorine-containing moiety often results in improved properties and biological activity compared to non-fluorinated analogs, making it a valuable component in the design and synthesis of novel drug molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 227184-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,1,8 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 227184-11:
(8*2)+(7*2)+(6*7)+(5*1)+(4*8)+(3*4)+(2*1)+(1*1)=124
124 % 10 = 4
So 227184-11-4 is a valid CAS Registry Number.

227184-11-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(1-fluoroethyl)-1H-pyrimidin-4-one

1.2 Other means of identification

Product number -
Other names 6-(1-fluoroethyl)-4-pyrimidone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:227184-11-4 SDS

227184-11-4Relevant articles and documents

4-fluoro-3-oxocarboxylic esters and process for producing the same

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, (2008/06/13)

The present invention is to provide 4-fluoro-3-oxocarboxylates represented by the following formula (1): wherein R1represents an alkyl group or an aryl group; R2and R3each represent a hydrogen atom or an alkyl group; and R4represents an alkyl group, and a process for preparing a 4-fluoro-3-oxocarboxylate represented by the above formula (1), which comprises allowing a 2-fluorocarboxylate represented by the following formula (2): wherein R1and R2have the same meanings as defined above; and R5represents an alkyl group, to react with a carboxylate represented by the following formula (3): wherein R3and R4have the same meanings as defined above, in the presence of a base.

6-(1-FLUOROETHYL)-5-IODO-4-AMINOPYRIMIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME, AND PEST CONTROLLERS FOR AGRICULTURAL AND HORTICULTURAL USE

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Page/Page column 7, (2008/06/13)

The present invention relates to a 6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compound represented by the following formula (1): ???wherein Ar represents a phenyl group, a naphthyl group, a thienyl group, an indanyl group or a 1,4-benzodioxan-6-yl group,

6-(1-fluoroalkyl)-4-pyrimidones and processes for producing the same

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Example 1, (2008/06/13)

The present invention is to provide a novel 6-(1-fluoroalkyl)-4-pyrimidone represented by the following formula (1): wherein R1represents an alkyl group; R2represents a hydrogen atom or an alkyl group; and R3represents a hydrogen atom, an alkyl group or a chlorine atom, which is important for a synthetic intermediate for aminopyrimidine derivatives which are useful as acaricides, fungicides or nematocides, and processes for producing the same.

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