229312-33-8

Basic information

• Product Name: 13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid
• Synonyms: 13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid;1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic acid, 13-oxo-;JYSLQCINSTWPIO-UHFFFAOYSA-N
• CAS NO: 229312-33-8
• Molecular Formula: C13H22N4O5
• Molecular Weight: 314.33758
• Mol File: 229312-33-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: 13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid(229312-33-8)
• EPA Substance Registry System: 13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid(229312-33-8)

Safety Data

• Hazardous Substances Data: 229312-33-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
13-oxo-1,4,7,10-Tetraazabicyclo[8.2.1]tridecane-4,7-diacetic Acid is used as an impurity in the synthesis of Gadoteridol for [application reason] MRI contrast enhancement. The compound is crucial in the production process, and its presence must be carefully managed to maintain the quality and safety of the final product.
In the context of Gadoteridol synthesis, the compound serves as a byproduct that needs to be controlled and minimized to ensure the purity and effectiveness of the MRI contrast agent. This is important for the accurate diagnosis and treatment of various medical conditions that require detailed imaging of internal structures.

Upstream product

• 79-08-3 bromoacetic acid 

Relevant articles and documents

1,4,7,10-tetraazacyclododecane-1,4-diacetic acid

1,4,7,10-tetraazacyclododecane-1,4-diacetic acid of formula (I): as well as its chelated complex salts with bi-valent metal ions having atomic numbers from 20 to 31, 39, 42, 43, 44, 49, or from 57 to 83, as well as their salts with anions of physiological

1,4,7,10-tetraazacyclododecane-1,4-diacetic acid derivatives as chelating agents

Compounds of formula (I) in which R is in which R is hydrogen, a straight or branched or cyclic C1-C6alkyl group, unsubstituted or substituted by 1 to 10 oxygen atoms, or a C1-C20alkyl group, optionally interrupted by a phenylene, in turn substituted by a straight or branched C1-C6alkyl group, unsubstituted or substituted by 1 to 3 C1-C7alkyl groups; the phenylene group being unsubstituted or substituted by alkoxy, carboxy, sulfamoyl, hydroxyalkyl, amino groups; as well as its complexes with a bi- or trivalent metal ion having an atomic number from 20 to 31, 39, 42, 43, 44, 49, or from 57 to 83, as well as its salts with anions of physiologically acceptable organic acids chelated complexes of these compounds are used as contrast agents for nuclear magnetic resonance imaging.