23358-42-1

Basic information

• Product Name: DL-VALINE ETHYL ESTER HYDROCHLORIDE
• Synonyms: DL-VALINE ETHYL ESTER HYDROCHLORIDE;H-DL-Val-OEt.HCl;ethyl DL-valinate hydrochloride;DL-ValineethylesterHCl;DL-Valine ethyl ester hydrochloirde;DL-Val-OEt·HCl
• CAS NO: 23358-42-1
• Molecular Formula: C₇H₁₅NO₂*ClH
• Molecular Weight: 181.66
• EINECS: 245-606-8
• Product Categories: Amino Acids & Derivatives
• Mol File: 23358-42-1.mol

Chemical Properties

• Melting Point: 94°C
• Boiling Point: 169.2 °C at 760 mmHg
• Flash Point: 42.7 °C
• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 3912411
• CAS DataBase Reference: DL-VALINE ETHYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DL-VALINE ETHYL ESTER HYDROCHLORIDE(23358-42-1)
• EPA Substance Registry System: DL-VALINE ETHYL ESTER HYDROCHLORIDE(23358-42-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 22-24/25
• Hazardous Substances Data: 23358-42-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
DL-Valine ethyl ester hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its role in the synthesis process is crucial, as it can be further modified or used as a building block to create more complex molecules with specific therapeutic properties.
Used in Chemical Research:
In the field of chemical research, DL-Valine ethyl ester hydrochloride is used as a reagent for [application reason]. Its unique chemical properties make it a valuable tool for exploring new reaction pathways, understanding the behavior of similar compounds, and developing novel synthetic methods.
Used in Organic Synthesis:
DL-Valine ethyl ester hydrochloride is used as a building block in organic synthesis for [application reason]. Its versatility allows it to be incorporated into a wide range of organic molecules, including pharmaceuticals, agrochemicals, and specialty chemicals, where it can contribute to the desired properties and functions of the final product.
Used in Analytical Chemistry:
In analytical chemistry, DL-Valine ethyl ester hydrochloride is used as a reference compound for [application reason]. Its well-defined structure and properties make it suitable for calibrating analytical instruments, validating analytical methods, and ensuring the accuracy and reliability of experimental results.
Overall, DL-Valine ethyl ester hydrochloride is a versatile compound with applications across various industries, including pharmaceuticals, chemical research, organic synthesis, and analytical chemistry. Its unique properties and reactivity make it a valuable asset in the development of new compounds and the advancement of scientific knowledge.

Upstream product

• 64-17-5 ethanol 
• 516-06-3 D,L-valine 

Downstream Products

• 13794-39-3 N-carbonyl-valine ethyl ester 
• 623547-64-8 4-isopropyl-1,3-dihydro-imidazol-2-one 
• 879553-76-1 N-(N-benzyloxycarbonyl-valyl)-valine ethyl ester 
• 53870-94-3 Z-Gly-Val-OH 
• 42998-42-5 N-benzyloxycarbonyl-DL-valine ethyl ester 
• 102600-59-9 N-[N^α-(toluene-4-sulfonyl)-histidyl]-valin-ethyl ester 
• 61131-42-8 N-benzoyl-valine ethyl ester 
• 61298-94-0 C₁₆H₂₂N₂O₅S 
• 132375-24-7 2-({Cyano-[3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-(4Z)-ylidene]-methyl}-amino)-3-methyl-butyric acid ethyl ester 
• 80589-60-2 2-(4-Cyanomethyl-benzoylamino)-3-methyl-butyric acid ethyl ester 
• 52895-36-0 Z-L-Ala-L-Val-OEt 
• 98820-33-8 Z-L-Ala-D-Val-OEt 
• 98807-10-4 Z-L-Pro-D-Val-OEt 
• 98807-03-5 Z-L-Pro-L-Val-OEt 

Relevant articles and documents

Anthranilic acid based CCK1 receptor antagonists: Blocking the receptor with the same 'words' of the endogenous ligand

The anthranilic acid diamides represent the more recent class of nonpeptide CCK1 receptor antagonists. This class is characterized by the presence of anthranilic acid, used as a molecular scaffold, and two pharmacophores selected from the C-terminal tetrapeptide of CCK. The lead compound coded VL-0395, endowed with sub-micromolar affinity towards CCK1 receptors, was characterized by the presence of Phe and 2-indole moiety at the C- and N-termini of anthranilic acid, respectively. Herein we describe the first step of the anthranilic acid C-terminal optimization using, instead of Phe, aminoacids belonging to the primary structure of CCK-8 and other not coded residues. Thus we demonstrate that the CCK1 receptor affinity depends on the nature of the aminoacidic side chain as well as that the free carboxy group of the alpha-aminoacids is crucial for the binding. The R enantiomers of the most active compounds represent the eutomers of this class of antagonists confirming thus the stereo preference of the receptor. Moreover this SAR study demonstrates that the receptor binding pocket, that host the aminoacidic side chain, results much more tolerant respect to that accommodating the indole ring. As a result, an appropriate variation of the aminoacidic side chain could provide a better CCK1 receptor affinity diorthosis.

Organosilicon synthesis of isocyanates: IV. Synthesis of isocyanates from aliphatic and alkylaromatic amino acid esters

Treatment of an alcoholic suspension of amino acids with trimethylchlorosilane yielded phenylglycine, valine, β-phenylalanine, and homovaline ester hydrochlorides. Their saccharin-catalyzed silylation with hexamethyldisilazane proceeds quantitatively and involves only one proton of the amino group. The best conversion of the amino acid esters to the corresponding isocyanates was achieved by phosgene treatment of their monosilyl urethanes, rather than of the silylated amino esters. Monosilyl urethanes are formed quantitatively by treatment of the amino acid ester hydrochlorides with the hexamethyldisilazane-CO2 system. The 1H NMR spectra show that monosilyl urethanes derived from α-and β-amino acid esters are characterized by intramolecular interaction of the silicon atom and the oxygen atom of the carboxy group. Nauka/Interperiodica 2007.