23420-32-8

Basic information

• Product Name: BOC-PHE-PRO-OH
• Synonyms: BOC-PHE-PRO-OH;Boc-Phe-Pro-OH≥ 99% (Assay);(Tert-Butoxy)Carbonyl Phe-Pro-OH
• CAS NO: 23420-32-8
• Molecular Formula: C₁₉H₂₆N₂O₅
• Molecular Weight: 362.42
• Mol File: 23420-32-8.mol
• Article Data: 26

Chemical Properties

• Melting Point: 155-157 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7))
• Boiling Point: 594.4°C at 760 mmHg
• Flash Point: 313.3°C
• Appearance: /
• Density: 1.225g/cm³
• Vapor Pressure: 5.63E-15mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: -15°C
• PKA: 3.51±0.20(Predicted)
• CAS DataBase Reference: BOC-PHE-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-PHE-PRO-OH(23420-32-8)
• EPA Substance Registry System: BOC-PHE-PRO-OH(23420-32-8)

Safety Data

• Hazardous Substances Data: 23420-32-8(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C19H26N2O5/c1-19(2,3)26-18(25)20-14(12-13-8-5-4-6-9-13)16(22)21-11-7-10-15(21)17(23)24/h4-6,8-9,14-15H,7,10-12H2,1-3H3,(H,20,25)(H,23,24)

Upstream product

• 7535-56-0 N-t-butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester 
• 147-85-3 L-proline 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 38017-89-9 t-butyloxycarbonyl-L-phenylalanyl-L-proline methyl ester 
• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 
• 3674-06-4 Boc-Phe-ONSu 
• 514214-66-5 (S)-tert-butyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-1-oxo-3-phenylpropan-2-yl)carbamate 
• 67729-36-6 Boc-Phe-O-COO-isoBu 
• 41324-66-7 H-Pro-OBzl 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1222098-01-2 C₃₈H₄₆N₄O₈ 
• 1427166-53-7 (S)-1-((S)-2-carboxypyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-aminium chloride 

Relevant articles and documents

N,O-Bis(trimethylsilyl)acetamide/N-hydroxysuccinimide ester (BSA/NHS) as coupling agents for dipeptide synthesis

A method using N,O-bis(trimethylsilyl)acetamide/N-hydroxysuccinimide ester (BSA/NHS) as coupling agents for dipeptide synthesis is descried. The coupling reaction between N-hydroxysuccinimide (NHS) esters and amines could be performed under mild conditions with N,O-bis(trimethylsilyl)acetamide (BSA) as coupling reagent and no additional acid/base is required. All byproducts and excessive reactants are water soluble or hydrolysable and easy to eliminate through water-washing at the purification stage. Moreover, all the reactants are inexpensive and widely used in conventional drug production.

Photoredox-Mediated Reaction of gem-Diborylalkenes: Reactivity Toward Diverse 1,1-Bisborylalkanes

The use of gem-diborylalkenes as radical-reactive groups is explored for the first time. These reactions provide an efficient and general method for the photochemical conversion of gem-diborylalkenes to rapidly access 1,1-bisborylalkanes. This method expl

Total Synthesis of the Cyclic Dodecapeptides Wewakazole and Wewakazole B

The cyclic dodecapeptides wewakazole and wewakazole B have been synthesized by a divergent strategy via a common tris-proline containing oxazole octapeptide and two separate bis-oxazole containing tetrapeptide units, followed by peptide coupling and macro